The 2026 Scientific Report brings science to life through engaging features of discovery, innovation and collaboration. Learn about the people, technology and breakthroughs advancing research in pediatric catastrophic disease. 🧪 Explore this year’s Scientific Report: bit.ly/4xkQQRS

Join @cmullighan.bsky.social, MBBS, MSc, MD, and leading experts for the 13th season of The Science of Childhood Cancer virtual lecture series beginning Aug. 13. The free 15-week series explores the latest discoveries in pediatric cancer research. Register now: bit.ly/4wDHCQJ 🧪

St. Jude is proud to host the @nature.com Conference, "Accelerating Pediatric Cancer Innovation: From Research to Real-World Impact," Nov. 11-12. Global experts will share advances in pediatric cancer research, innovative therapies and strategies to strengthen health systems worldwide.

Their work spans brain tumor diagnosis, pharmacogenomics, survivorship care and rare blood disorders, helping clinicians apply the latest evidence in ways that are practical, reliable and relevant for patient care.

How do clinicians turn a growing body of biomedical evidence into accurate diagnoses and effective treatment decisions? St. Jude researchers are helping answer that question by writing and updating international guidelines across pediatric diseases.

Rare inherited diseases can result from many different mutations in the same gene, which makes traditional drug development difficult. Learn how antisense oligonucleotides, or ASOs, offer a more flexible path by targeting RNA before a harmful protein is made.

Congratulations to Amar Gajjar, MD, on receiving the ISPNO Lifetime Achievement Award. His pioneering work in childhood brain tumors has helped transform care, improve outcomes and inspire a generation of neuro-oncology leaders. #ISPNO2026

St. Jude welcomes Heather Currier Hunt as senior vice president for the St. Jude Leadership Academy (SJLA), which manages leadership development programs. She will help evolve SJLA to support the institution’s growing workforce and global impact. ow.ly/s7Ws50Zirb0

On World Sickle Cell Day, we are sharing Donte’s story. Donte has lived with the disease since infancy, but after Akshay Sharma, MD, introduced him to gene therapy, a new path forward became possible.

St. Jude has been redesignated as the first and only WHO Collaborating Centre dedicated to childhood cancer. The milestone advances joint work with WHO to expand access to quality cancer care, strengthen health systems and improve outcomes for children worldwide. Learn more: ow.ly/jcj250ZcMJn

During Cancer Immunotherapy Month, we highlight decades of progress at St. Jude, supported by the infrastructure and leading scientific expertise advancing immunotherapy. Learn more about Center of Excellence for Pediatric Immuno-Oncology: ow.ly/hhrI50ZchnH

DNA provides the blueprint for biology, but epigenetics determines how it is used. St. Jude researchers are studying how these regulatory systems control gene activity and how their disruption contributes to diseases including cancer, neurologic disorders and blood diseases.

National Cancer Survivors Day honors survivors and the progress that helps more children move beyond treatment. Ashley Gault, RN, was diagnosed with hepatoblastoma at 10 months old and treated at St. Jude. After nursing school, she returned as a nurse, bringing her journey full circle.

During Cancer Immunotherapy Month, we recognize the work of the St. Jude Center for Excellence in Pediatric Immuno-Oncology (CEPIO). CEPIO connects many departments and the Children’s Good Manufacturing Practice (GMP) facility to move new cell therapies toward clinical studies.

This work is helping researchers understand cell identity, and how it can be corrupted in diseases, which is informing directions for future therapeutic opportunities. Read more: ow.ly/wVYb50Z4glp

Cells can contain the same DNA “instructions” but become different cell types and behave differently. Scientists are studying the role that epigenetic regulation plays in this process.

Today we mark the eighth anniversary of St. Jude Global and its work to address disparities in outcomes for children worldwide. Through collaboration with WHO and global partners, St. Jude Global expands access to care while sharing knowledge, technology and expertise.

At the World Health Assembly in Geneva, St. Jude convened researchers, policymakers and people with lived experience to advance shared priorities for children’s health. Decisions at this level influence policies, health systems and access to care worldwide. #WHA79

On Clinical Trials Day, we recognize the essential role clinical trials play in advancing the St. Jude mission. Our investigators study new treatment strategies, refine existing approaches and work to deliver more precise care for patients.

The Global Platform for Access to Childhood Cancer Medicines is expanding more than treatment access. In Ghana and Nepal, improved data systems and cancer registries are helping leaders better understand disease burden, plan care and identify gaps. ow.ly/j97t50YYVbP

Recent findings from St. Jude combine clinical, imaging and molecular data to guide treatment for H3 G34–mutant diffuse hemispheric glioma (DHG), helping move beyond strategies designed for adults to treat this rare brain tumor in children. ow.ly/LE9N50YXCkm #BTAM #StJudeResearch

Xin-yan Chen, PhD, a postdoc in the lab of Chunliang Li, PhD, Tumor Cell Biology, shared research on KMT2A-rearranged leukemia earning top honors at the 12th St. Jude Comprehensive Cancer Center Postdoctoral Symposium. Learn more about Chen: https://ow.ly/W2H050YW9mV

Hongbo Chi, PhD, Department of Immunology chair, has been elected to the National Academy of Sciences in recognition of his field-defining research connecting immunology, metabolism and adaptive immunity. ow.ly/Hkvm50YUJyl

Julie R. Park, MD, Oncology chair, shared a powerful look at next-generation therapies for childhood solid tumors as the #ASPHO2026 Oncology Luminary Speaker.

Kim Nichols, MD has received the 2026 George R. Buchanan Lectureship Award from ASPHO, recognizing leadership in pediatric hematology/oncology and advances in hereditary cancer risk care. #ASPHO2026

St. Jude is proud to sponsor the ASPHO Early Career Roundtable Luncheon today at #ASPHO2026, supporting training and mentorship for the next generation of pediatric hematology/oncology clinicians and physician-scientists. #ASPHO #PedsHemeOnc

At the conclusion of #AACR26, we are highlighting our St. Jude graduate students, fellows and postdocs who presented their research. #StJudeResearch

Jake Friske, Biomedical Sciences PhD student, presented this research titled “A conserved enhancer locus in ecDNA and HSRs activates MYC transcription in group 3 medulloblastoma” in the late-breaking poster session at @theaacr.bsky.social. Friske is a first author of the Cancer Research paper.

At #AACR26, Charalampos Kalodimos, PhD, chaired and presented “Conformational landscapes of protein kinases and their therapeutic exploitation” in the Structural Insights to Cancer Biology and Therapy major symposium. #StJudeResearch

St. Jude and the Damon Runyon Cancer Research Foundation awarded the 2026 fellowships to a class of early-career researchers. Five investigators will receive four years of funding to pursue innovative projects in pediatric cancer research. https://ow.ly/8AMk50YNwqJ