Diabetologia
@diabetologiajnl
We publish high-quality, cutting edge articles on all aspects of diabetes, from basic science through translational work to clinical research
A DFU core descriptor set, a minimum set of descriptors to be measured in all studies evaluating interventions for people with diabetes-related foot ulceration, has been developed #Diabetes #DiabetesResearch #DFU link.springer.com/article/10.1... 🔓
#WeightLoss, #PhysicalActivity, #Nutrition, and #Sleep optimisation remain the cornerstones of #MASLD treatment. Read our review to see how #lifestyle change is not an adjunct to care, but the driving force behind meaningful and durable clinical outcomes link.springer.com/article/10.1... 🔓
New review on imaging in MASLD: from ultrasound and CT to advanced MR and PET–comparing performance, accessibility and clinical utility for assessing steatosis and fibrosis. #MASLD #LiverImaging #MRI #Ultrasound link.springer.com/article/10.1... 🔓
A review of dementia risk factors in #T2D: a probabilistic model suggests opportunities for prevention across the lifespan #dementia #smallvesseldisease #vascularcognitiveimpairment #diabetes link.springer.com/article/10.1... 🔓
Plasma-induced transcriptional profiling defines two immune subgroups in type 1 diabetes that associate with differing progression rates and responses to anti-CD20 and CTLA4-Ig. #Type1Diabetes #Immunotherapy #PrecisionMedicine #TrialNet link.springer.com/article/10.1... 🔓
Administering prandial insulin 15 min prior to meal intake began (compared with 15 min after) reduced postprandial hyperglycaemia and increased myocardial microvascular blood flow in people with type 1 diabetes. link.springer.com/article/10.1... 🔓
From early electron microscopy of insulin granules to 3D islet reconstructions, this review follows the evolution of islet ultrastructure imaging and looks ahead to link structure with function in diabetes. link.springer.com/article/10.1... 🔓 @plid-info.bsky.social @hhmijanelia.bsky.social
Higher abdominal and liver fat are linked to lower hippocampal insulin sensitivity with ageing, especially in women. #DiabetesPrevention #WomensHealth #BrainInsulinResistance link.springer.com/article/10.1... 🔓
The role of GIP in splanchnic blood flow regulation is confirmed in people with type 2 diabetes, underpinning the importance of GIP in postprandial physiology despite its weak glucose-lowering effect #T2D #DiabetesResearch link.springer.com/article/10.1... 🔓
History of #infertility was associated with a 30% greater risk of developing #diabetes, with specific infertility diagnoses such as ovulatory and tubal factors also associated with greater risk #T2D #DiabetesResearch link.springer.com/article/10.1... 🔓
Maternal type 1 diabetes is associated with delayed early-life maturation of the breastmilk microbiome. This finding contributes to our understanding of breastmilk microbial maturation relevant to gut and immune development. #T1D #Microbiome #Immunology link.springer.com/article/10.1... 🔓
Surrounding #T2D diagnosis, older adults undergo dynamic body composition remodelling: an inverted U-shaped BMI trajectory, continuous visceral fat accumulation and probably accelerated muscle depletion link.springer.com/article/10.1... 🔒
Close to half of islet secretory function retained after total pancreatectomy with islet autotransplantation (TPIAT) independent of preoperative glycaemic status & prior surgery. CGM-derived glycaemic control is correlated with islet secretory function after TPIAT link.springer.com/article/10.1... 🔓
Our August issue is online now! link.springer.com/journal/125/... @easdnews.bsky.social @springernature.com @springermedicine.com
Why does liraglutide work differently across patients? Metabolic state shifts its mode of action from brain tanycyte pathways in health to direct islet effects in #prediabetes. This offers a new framework for smarter #GLP-1R agonist use #T2D link.springer.com/article/10.1... 🔒
In this post-pandemic appraisal of the published literature, the authors explore the potential bidirectional relationship between COVID-19 and diabetes. #COVID19 #DiabetesResearch link.springer.com/article/10.1... 🔓
#Metabolomics reveals key differences between LADA and #T1D, highlighting disease heterogeneity. #Tryptophan metabolism varies across #autoimmune conditions correlating positively with #β-cell function, suggesting role in disease progression. link.springer.com/article/10.1... 🔓
Randomised study in adults ≥65 with T1D shows that MiniMed 780G safely improves time in range and HbA1c over 12 months, without more hypoglycaemia or retinopathy, and with trend towards better microvascular function #T1D #DiabetesResearch link.springer.com/article/10.1... 🔓
Up front & free to read in our July issue #editorspicks: Endoplasmic reticulum–mitochondria contact sites are signalling hubs connecting nutrient sensing and GLP‑1 secretion in L cells of the mouse gut: from physiology to obesity and type 2 diabetes doi.org/10.1007/s001...
Autoantibody screening in children who are first-degree relatives of people with type 1 diabetes: multicentre prevalence, determinants and post-screening parent–child anxiety #T1D #DiabetesResearch link.springer.com/article/10.1... 🔓️
Up front & free to read in our July issue #editorspicks: Integrated intraocular–plasma proteomics reveals conserved biomarkers for diabetic retinopathy progression: a multi‑fluid biopsy study doi.org/10.1007/s001...
Up front & free to read in our July issue #editorspicks: The glycaemic response to morning fasted resistance exercise is more consistent than the response to afternoon fed resistance exercise for adults with type 1 diabetes: a randomised crossover comparison doi.org/10.1007/s001...
Up front & free to read in our July issue #editorspicks: From pancreas and islet resources to diabetes insights doi.org/10.1007/s001...
Beyond lipids, altered #GlucoseMetabolism and hormonal dysregulation drive #MASLD progression to #MASH via adipokine-mediated signalling, highlighting #LiverDisease as a multi-organ disorder driven by multi-substrate metabolic reprogramming link.springer.com/article/10.1... 🔓️ #Fibrosis
Up front & free to read in our July issue #editorspicks: Perspectives on human adipose tissue: from cellular mechanisms to clinical complications doi.org/10.1007/s001...
How does GLP-1 boost insulin release? GLP-1 acts through type IIB PKA to mediate its effects on KATP channel activity, Ca²⁺ channel function and insulin granule morphology, key mechanisms identified by Rui Liu et al link.springer.com/article/10.1... 🔓️
Impacting lives of people with diabetes in India. A review by Dr V. Mohan based on his EASD Diabetes Global Impact Prize lecture 2025 provides valuable lessons for low- and middle-income countries regarding diabetes management using low-cost technology link.springer.com/article/10.1...
Hypoglycaemia rates do not differ between genders in the Hypo-METRICS study, but women report more symptomatic hypoglycaemia and a different symptom profile to men link.springer.com/article/10.1... 🔓️