The EMBO Journal
@embojournal
Non-for-profit publication of research in molecular, cell & organismal biology - as part of @embopress.org Fast-fair-transparent / Open Access / Open Science
ISSUE 15 Perspective: immunosuppressive neutrophils Review: cryptic lncRNA translation Method: scalable phosphotyrosine proteomics Resource: SenFlag senescence signature Assembly: RNA exosome, ATP synthase, SecYEG membrane protein insertase Cover: Ikuo Suzuki et al link.springer.com/journal/4431...
Redefining ecological opportunity for evolution in the Anthropocene: Lutz Becks, @reefgenomics.bsky.social and colleagues comment on the concept of timescale mismatch between the rates of environmental changes and evolutionary processes link.springer.com/article/10.1...
Looking for weekend reading? New review by @kei-jokura.bsky.social and @jekely.biologists.social.ap.brid.gy revisits nerve nets, their functional organization, and evolutionary implications link.springer.com/article/10.1...
ISSUE 14: Review on skin aging SPACA9 and MNMIP1 on spermatid manchette microtubules DNA damage-activated kinase in bacterial immunity MORC3 regulates interferon via tandem repeat enhancer Cover: Sekler, Shirihai and coworkers link.springer.com/journal/4431...
How to tether descriptive ‘cell atlases’ to biological mechanisms? Bin Zhou proposes intersectional genetics as a novel cell-type-specific strategy for enhanced marker tracing and cell fate control in animals link.springer.com/article/10.1...
In issue 13: Review: roles of nonsense-mediated RNA decay New SUMO ligase in plant immunity Mitochondrial calcium uptake in Alzheimer’s progression Mechanosensitive FHL2 and microtubule-actomyosin crosstalk Cover: Zheng, Hu, Long et al link.springer.com/journal/4431...
New review: The identity crisis of cryptic lncRNAs – Leoš Valášek and colleagues discuss how and when non-coding RNAs translate into small peptides link.springer.com/article/10.1...
This week: are you attending #EESMicrotubules ℅ @events.embl.org? As always, our @embojournal.org cytoskeleton editor Ieva Gailite will be there too, and is looking forward to discussing your data with you!
Issue 12: Comment on spatial metabolomics Review: Host/transposable element coexistence Method: One-step generation of T-cell receptor knock-in mice Phase separation of bacterial transcription terminator Cover: Sabrina Chumpen, @dmitryshvarev.bsky.social et al link.springer.com/journal/4431...
Human immunosuppressive neutrophils: recent answers to old and new questions New Perspective Article by Patrizia Scapini, Marco Cassatella et al link.springer.com/article/10.1...
Issue 11 Highlight: Clean AIFM1 cut by OMA1 curtails respiration Review: Antibiotic-induced gut microbiome dysbiosis Peroxisome ether lipids & lysosomal exocytosis Substrate allostery rules prothrombinase processivity De nove piRNA immunity upon retrovirus insertion link.springer.com/journal/4431...
Remarkable: this splendid @embo.org cake prepared by the local organizers!
The end of a great meeting: #EMBOevents #EMBOtelomere Our editor @hvodermaier.bsky.social presents the @embojournal.org poster prize to winner Valeria Rubeo from @crcm.bsky.social - congratulations! meetings.embo.org/event/26-tel...
New review article: Jing-Dong Han and colleagues discuss mechanisms and evaluation of skin aging, as well as strategies for rejuvenation link.springer.com/article/10.1...
In issue 10: Convergent evolution of aerobic fermentation CIN promotes migration & invasion via EFEMP1 secretion SenSet resource defines cell-type specific senescence signatures ... Cover: @franbottanelli.bsky.social and colleagues link.springer.com/journal/4431...
Host-transposable element coexistence: a matter of resistance, tolerance and trade-off Read this new review by Séverine Chambeyron, Charlotte Grimaud, Mikiko Siomi et al link.springer.com/article/10.1...
Beyond quality control: Kun Tan and Miles Wilkinson review biological roles of nonsense-mediated RNA decay and how they may be targeted by therapeutic interventions link.springer.com/article/10.1...
New commentary in our Metabolism collection: Prasad Phapale @au.dk discusses design, pitfalls and data interpretation in spatial metabolomics link.springer.com/article/10.1...
Issue 9: Review: controls of quantitative gene expression and epigenetic memory Resource: Cancer cell responses to USP9x inhibitors Embryonic transposable element regulation by TBP Ki-67 shapes nucleolus via chromatin anchoring Cover: S. Nakamura, N. Koizumi et al link.springer.com/journal/4431...
Read our new Review Article on antibiotic-induced gut microbiome dysbiosis: Michael Knopp, Camille Goemans et al discuss risks and strategies for mitigation link.springer.com/article/10.1...
ISSUE 8 Highlights: Feeder-free stem cell cultures Sperm age & RNA code Perspective: ensuring transcript fidelity in transgene expression Defining STI1 domain roles in ubiquilin Dual phage inhibition of bacterial virulence & defense Cover: Junichi Ikenouchi et al link.springer.com/journal/4431...
Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes @hittingerlab.bsky.social , @linder-surprise.bsky.social et al show how distinct genetic routes can converge on the same genetic outcome link.springer.com/article/10.1...
How come giant mimivirus virions retain icosahedral symmetry like smaller viruses? Chantal Abergel, Hugo Bisio @molbiolgv.bsky.social et al use bioinformatics, genetics & interactomics to elucidate spatial & functional organization of mimivirus virion morphogenesis link.springer.com/article/10.1...
A conserved leader–repeat hairpin prevents processing of the first CRISPR repeat, suppressing extraneous crRNA production and preserving Cas13-mediated immunity Chase Beisel @helmholtz-hiri.bsky.social and coworkers link.springer.com/article/10.1...
In ISSUE 7: Perspective: Molecular evolution of animal aging Review: eIF3 roles in cells and disease Sorting nexins & hybrid endosomal coats Purine metabolism supported by microcephaly protein WDR62 Cover: Biao Gong and colleagues link.springer.com/journal/4431...
Happening soon - meet our immunology editor Ioannis Papaioannou at @keystonesymposia.bsky.social #InnateImmunity in beautiful Banff! #KSInnateImmune26 hubs.la/Q03TCrHw0
Our cancer editor Daniel Klimmeck will be in Bergamo for the EACR Conference ‘The Tumour Ecosystem’, and is looking forward to learning about your work there! @helloeacr.bsky.social eacr.org/conference/t...
Our SPECIAL ISSUE on MOLECULAR EVOLUTION & ECOLOGY is out! Editorial: @yehumoran.bsky.social, @berndpulverer.bsky.social et al Reviews on Asgard archaea, epimutations, giant-virus/host dynamics, smartphone analogy for animal origins… …& many related primary articles link.springer.com/journal/4431...
Asgard #archaea: have we found our microbial ancestors? New review (also for newcomers to the field!) by Christa Schleper and Thiago Rodrigues-Oliveira link.springer.com/article/10.1...
Featured in issue 5: Mitotic entry—Bora takes Polo to Aurora Tyrosine kinase targeting in Tasmanian devil cancer—cover by Morrigl and colleagues Proteome/transcriptome uncoupling in cellular quiescence Unique compartmentalization of holocentric silkworm chromosomes link.springer.com/journal/4431...