Could the sound outside your home influence your Parkinson's disease risk? Sørensen et. al. describe a new paper JAMA Neurology whether years of living in noisier environments are associated w/ a higher risk of developing Parkinson's disease. Seems there is something 'in the air.' cutt.ly/wytjYp8H

Can replacing lost dopamine cells finally move us toward restoring the Parkinson’s brain? Paul, Barker and colleagues describe in new paper in Nature Medicine the first 12-month results of the STEM-PD phase 1/2 trial. Good results, one fatality due to immunosupression. www.nature.com/articles/s41...

How do you choose the best sleep sensor for Parkinson's disease and neurodegenerative disorders? Remember that total sleep time is really important and we tell folks in my clinic to shoot for ~6-8 hours if possible. Nice discussion in this paper. www.nature.com/articles/s41...

Blood biomarkers are transforming how we diagnose Alzheimer's disease. However, this study reminds us that no diagnostic test performs equally well in every clinical setting. A history of TBI appears to alter the biology enough that these promising blood tests become less reliable. cutt.ly/lyw3fTfv

Are you checking out all the heading of the ball in the World Cup? What happens to p-tau after a header? New paper in JAMA Neurology about how heading soccer ball during real-world amateur matches was associated w/ short-term increases in blood biomarkers linked to neural injury. cutt.ly/4yecT3wP

Do DBS candidates have less Lewy bodies in their brains? Biopsies taken during the DBS procedure could inform this question. New paper in npj PD the results from the Sinai Living Brain study. This was an intriguing observation in a cohort of carefully screened folks w/ DBS for Parkinson’s disease.

Multiple sclerosis is entering a new era: from controlling relapses to preventing progression. Progression independent of relapse activity means that disability can slowly accumulate even when there are no obvious attacks or new MRI lesions. This concept is reshaping how we think about MS.

What do folks with late-stage Parkinson's disease die from? The answer may change how we care for the final years of life. Decade long study followed 107 individuals living w/ late stage Parkinson's disease and examined mortality, causes of death and factors associated w/ survival.

When Tourette syndrome is more than tics in adults: the hidden impact of depression and ADHD on quality of life. New paper in Movement Disorders Clinical Practice how psychiatric symptoms influence tic severity and quality of life in 227 adults living w/ Tourette syndrome from Canada and France.

Save the dates for the upcoming DBS Think Tank, taking place September 16–18, 2026. We are looking forward to another year of engaging discussions and collaboration in the field of DBS. Stay tuned for additional details, including the Zoom registration link and full program information.

Focused ultrasound and pallidotomy: what can lesions teach us that DBS cannot? Zaidel and colleagues described in a fascinating paper (2008) in the European Journal of Neuroscience how prior pallidotomy lesions altered the physiology of the subthalamic nucleus years later in folks living w/ PD.

When the scale drops in Parkinson's disease, should we worry? Unintentional weight loss means losing weight without trying. In PD it may signal changes in nutrition, swallowing, metabolism, cognition or disease progression: All hands on deck. movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...

Can we prevent Parkinson's disease before it begins? Well, the new 8 C's framework just dropped in a new paper and it aims to change the conversation. www.nature.com/articles/s41...

A remarkable life in Parkinson's disease and movement disorders: remembering Regina Katzenschlager. Susan Fox and colleagues describe, in a moving tribute, in Movement Disorders the extraordinary career and contributions. movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...

Could a blood test help track tau pathology in BPAN? Plasma pTau217 levels were markedly elevated in children and adolescents w/ Beta-Propeller Protein-Associated Neurodegeneration (BPAN), a rare neurodegenerative disorder caused by WDR45 mutations.

Can deep brain stimulation help speech in dystonia? New paper in Movement Disorders how voice and speech symptoms change following deep brain stimulation (DBS) in dystonia: retrospective study, a systematic review, and a meta-analysis.

Can genetics and brain pathology finally explain why Parkinson's is not one disease? One of the largest global brain bank studies ever assembled, combines genetics, pathology, and clinical data from more than 3,300 individuals with Parkinson's disease and related disorders. cutt.ly/Ot9FV6kR

The Parkinson's Plate: A Health and Diet Guide to Manage Your Journey. Pre-order is now open for October 1st on Amazon. cutt.ly/Jt2RlrzH

Can spinal manipulation prevent chronic low back pain? A new trial challenges some assumptions. Spoiler alert: What happens between visits may matter as much as what happens during a treatment session.

Why do some folks fail deep brain stimulation screening? New paper in Movement Disorders Clinical Practice shares the largest multidisciplinary analysis to date examining why some folks with Parkinson's disease, essential tremor, and dystonia do not ultimately move forward with DBS surgery.

The levodopa paradox: a medication, a biomarker, and a prognostic clue? Do you know how levodopa responsiveness relates to diagnosis, prognosis, and underlying pathology across Parkinson's disease (PD), multiple system atrophy (MSA), and progressive supranuclear palsy (PSP). Spoiler: It is awesome.

Ebola survivors may carry neurological scars for years after the infection is gone. Bridgette Billioux and colleagues describe in a new paper in JAMA Neurology the neurological manifestations observed in adult survivors of Ebola virus disease followed for more than 7 years in Liberia.

Childhood brain development may be shaped more by neighborhood opportunity than IQ. Marek, Dosenbach and colleagues describe in a new paper in Science how socioeconomic factors may be the strongest predictors of brain organization in childhood, even exceeding measures such as IQ and psychopathology.

When tremor comes back after focused ultrasound: should you re-lesion or switch to DBS? New paper in Tremor and Other Hyperkinetic Movements on how DBS can successfully rescue recurrent essential tremor following MRI-guided focused ultrasound thalamotomy.

The Parkinson’s Plan is now available in Spanish. El plan para vivir con la enfermedad de Parkinson: Un nuevo enfoque para prevenirla y tratarla by RAY DORSEY, MICHAEL S. OKUN En esta obra, Ray Dorsey y Michael S. Okun. cutt.ly/Xt2esco3

Can sitting too much change how you perceive your balance in Parkinson’s disease? Spoiler alert: Some folks underestimate their abilities and restrict activity, while others may overestimate their abilities and increase fall risk. New paper in npj Parkinson’s Disease.

Can healthy eating prevent Parkinson's disease? A new 32-year study challenges assumptions. Chen and colleagues describe in a new paper in Movement Disorders whether adherence to eight healthy dietary patterns influences the risk of developing Parkinson's disease.

Can we measure Parkinson's disease progression years before diagnosis? Monica Roascio and colleagues describe in a new paper in Brain how clinical changes in REM sleep behavior disorder (RBD) may be tracked years before the emergence of overt Parkinson's disease or dementia.

Can fecal microbiota transplantation overcome antibiotic resistant superbugs? Spoiler alert: Not in this study. A single FMT treatment did not eliminate multidrug-resistant organisms (MDROs) from the gut in folks w/ gastrointestinal diseases. cutt.ly/ht0Wqwt3

Can a brain MRI reveal the biology behind Parkinson’s disease? New paper in Annals of Neurology how diffusion MRI findings relate to α-synuclein seed amplification assay (SAA) status in early Parkinson’s disease. onlinelibrary.wiley.com/doi/10.1002/...