Press release on a new award for our lab! qdnl.nl/news/quantum...

Excited to share that Vahid Sheikhhassani is presenting our lab’s latest advances in biomolecular condensate research at the Dutch Medicine Days! Looking forward to discussing new insights and connecting with colleagues across the field. #ChemSky #FIGON

Our quantum sensing research is featured on the front page of the Leiden University website today! Thanks to our team and collaborators for their dedication and contributions to this exciting work. www.universiteitleiden.nl/en/news/2026... #QuantumSensing #QuantumTechnology #ChemSky

Through a series of papers, we demonstrated the applicability of scanning probe microscopy to biomolecular condensate analysis! Droplet fusion: doi.org/10.1038/s414... Droplet rheology: doi.org/10.1016/j.xc... doi.org/10.1016/j.xp... Droplet-cell interaction: doi.org/10.1016/j.ce... #ChemSky #AFM

This week, we installed a first-of-its-kind quantum sensing platform in our lab! As part of our lab’s mission to advance #interdisciplinary research, we’re bringing #quantum sensing into #pharmacology. #ChemSky

With my team this Friday evening, concluding our lab work with an outing in the city!

A new study by Runfeng Lin & Sebastian Ahnerton from Cambridge University on the application of Circuit Topology in Protein Science: "Millisecond Prediction of Protein Contact Maps from Amino Acid Sequences" www.biorxiv.org/content/10.6... #ChemSky #Topology #StructuralBiology #Bioinformatics

Delighted to share our new study, "Topological Investigation of Protein Folding and Intrinsic Disorder". We ask whether topology provides a unifying structural language across the order–disorder continuum! doi.org/10.64898/202... #ChemSky #Protein #IDP #Topology #Biophysics

RNA topology: from simple loops to complex circuits chemrxiv.org/engage/chemr... #ChemSky #RNA #Biophysics

Learning capacity and function of stochastic reaction networks iopscience.iop.org/article/10.1... #ChemSky #Network #Physics #Stochasticity #Learning

On circuit topology of knots! Circuit topology for bottom-up engineering of molecular knots doi.org/10.3390/sym1... A tile model of circuit topology for entangled biopolymers www.nature.com/articles/s41... Polynomial invariant of molecular circuit topology doi.org/10.3390/sym1... #ChemSky #knot

Our protocol on "Scanning probe microscopy for rheological analysis of biomolecular condensates" is now available for interested users! doi.org/10.1016/j.xp... #ChemSky #Biphysics #Biomolecular_Condensates #IDP #Rheology #AFM

Vasily from our team was invited to present at the #NRRN meeting on “Conformational Dynamics and Chromatin Assembly of #Glucocorticoid Receptor Using Topological Modeling and Single-Molecule Analysis.” Looking forward to connecting with researchers on advances in nuclear receptor research. #ChemSky

We discovered that the "orphan" nuclear receptor Nur77 binds DNA under regulation by #glucocorticoid receptor & glucocorticoids. The synthetic glucocorticoid dexamethasone directly interacts with Nur77, revealing a new function for this drug & a potential ligand for Nur77. doi.org/10.1101/2025...

We’re excited to share our new #PyMOL plugin for protein topology analysis, now available! doi.org/10.1101/2025... Link to the report and the GitHub repository: We’d appreciate your feedback — please try it out in PyMOL and report any bugs or suggestions! #ChemSky #IDP #Topology #Bioinformatics

Our postdoctoral researcher Aida Naghilou presented our lab’s development of SPM-based technology for biomolecular condensate analysis at the Erwin Schrödinger Institute during the workshop “Charged Soft Matter: Bridging Theory and Experiment”! www.youtube.com/playlist?lis... #ChemSky #SoftMatter

PhD student Vasily Akulov from our group is presenting our collaborative research with Eva Estébanez-Perpiñá’s group at the EMBO Workshop in Palermo, Italy! meetings.embo.org/event/25-str... #EMBO #StructuralBiology #IDP #Topology

On extracellular #biomolecular condensates! We demonstrate that phase-separated #condensate #droplets can form and function in the #extracellular environment and may interact with cells! www.sciencedirect.com/science/arti... #CellBiology #Biophysics #ChemicalEngineering #SyntheticBiology #ChemSky

Check out our research on Semantic Topology at the 63rd Annual Meeting of the Association for Computational Linguistics (ACL 2025) in Vienna next week! #ACL2025 #Interdisciplinary #Semantics

Semantic Topology: a New Perspective for Communication Style Characterization aclanthology.org/2025.finding... #Linguistics #NLProc #ACL2025NLP #ACL2025

On disordered topologically compact states in intrinsically disordered proteins! We explored this concept in the context of the human Glucocorticoid Receptor. pubs.acs.org/doi/10.1021/... #ChemSky #IDP #Protein #Biophysics #Topology #CompChem

New Boltzmann Medalist Mehran Kardar at StatPhys29 in Florence, showing the first handmade slide that led to the #KPZ equation. #StatisticalPhysics #Physics Photo: Andrea Gabrielli

Team snapshot after our regular group meeting — this time with a great talk by Muriel Hammond on intrinsically disordered proteins!

For those interested in topological analysis of biomolecular condensates! Article 1: link.springer.com/article/10.1... Article 2: www.sciencedirect.com/science/arti... #Topology #Condensate #PhaseSeparation #Aggregation #ChemSky #Biophysics #Polymer #Nanoscience

PhD student Laurens Heling from my laboratory will be presenting a the #LACDR Spring Symposium! "Single Molecule Analysis Reveals Allosteric Regulation of #Androgen #Receptor DNA Binding​" #SingleMolecule #Biophysics #Endocrinology

At NWO Physics conference in Veldhoven! Our team presented on biomolecular condensates and circuit topology! #NWO #Physics #NWOPhysics #SoftMatter #Topology #Materials

On topological analysis of single-cell HiC data! #genome #chromatin #bioinformatics #SingleCell link.springer.com/protocol/10.... www.sciencedirect.com/science/arti...

"Substance P: From Pain to Cancer" is now in print! We contributed a chapter on immunobiology and pharmacology of neuropeptide substance P! www.sciencedirect.com/science/arti... #immunology #neurology #neuropeptide #pharmacology #ChemSky

While human #proteins span a wide range of molecular weights, from approximately 0.26 to 4000 kDa, human chemokines are restricted to a narrow range of about 8 to 14 kDa. We asked whether there might be an optimality in #cellular #communications. arxiv.org/abs/2412.00771 #Immunology #Chemokine

Our work on the cover of Materials Advances! Single-cell analysis of innate immune cell mechanics: an application to cancer immunology pubs.rsc.org/en/content/a... #immunology #innateimmunity #immunomechanics #mechanobiology #SingleCell