BD²

@bipolardiscoveries

BD² is a collective force shortening the time it takes to get from scientific breakthroughs to improved clinical care for bipolar disorder. bipolardiscoveries.org

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BD²@bipolardiscoveries· 12d

🧬 1,500 participants. 12 sites. Whole-genome sequencing underway. BD²’s Integrated Network combines genetic, clinical, and real-world data to advance research and outcomes for people with #BipolarDisorder. Hear from Cara Altimus, PhD, & Benjamin Neale, PhD, on The Genetics Podcast: bit.ly/3SiTBnj

BD²@bipolardiscoveries· 14d

⏰ One week left to apply for the BD² Data Science Fellowship. Postdocs can apply for up to $125,000 per year over two years to analyze existing BD² datasets and advance data-driven #BipolarDisorder research. Apply by July 31: bit.ly/4ajk768

BD²@bipolardiscoveries· 19d

🚀 We’re hiring a Director of Partnerships to build BD²’s development program and help fuel breakthrough discoveries in bipolar disorder research. We’re looking for an exceptional leader to shape our strategy, grow our community, and scale our impact. 🔗 Apply: bit.ly/3TaXrQ4

A graphic with a blue textured background. A white box in the center with a lime green outline reads “We’re Hiring: Director of Patnerships” with the subheading “We’re looking for a development professional to scale our impact.” A lime green button in the bottom right corner says “Apply Now.”

BD²@bipolardiscoveries· 28d

🧠 BD² PI @ignaciosaezphd.bsky.social and his team are using deep brain stimulation and epilepsy-based brain recordings to better understand the circuits that drive mood changes in bipolar disorder. The more we learn about these circuits, the closer we get to treatments tailored to brain biology.

BD²@bipolardiscoveries· Jul 7

🔬 BD² Lead PI Ziad Nahas, MD, MSCR, and his team at @umnbme.bsky.social are using advanced tools to better understand the individual neurobiological patterns that underlie mood episodes. This precision matters for diagnosis, prediction, and ultimately, more personalized care.

BD²@bipolardiscoveries· Jun 30

Siloed data limits what we can learn. Real progress in bipolar research comes from integration — aligned data collection, collaboration across teams, and transparent public release. 🔗 www.bipolardiscoveries.org/our-work/data-release ▶️ bit.ly/4cJpyMk

BD²@bipolardiscoveries· Jun 11

🧬 Genetic discovery is transforming our understanding of bipolar disorder. Now, it’s about translating that knowledge into better care. On The Genetics Podcast, Cara Altimus & Benjamin Neale discuss how genetics + longitudinal data can drive more precise diagnosis & treatment. 🎧 bit.ly/3SiTBnj

BD²@bipolardiscoveries· Jun 9

🧠 “By releasing these data to the public, we can massively expand the capacity to generate insights—beyond any single investigator or network.” — Katherine Burdick, PhD, on the BD² Integrated Network data release 🧬Explore the release: bit.ly/4vLaaHO ▶️Watch more: bit.ly/4cJpyMk

BD²@bipolardiscoveries· May 28

We’re growing 🌱 Hiring a Science Communications Manager to help shape BD²’s voice and translate complex bipolar disorder research into clear, compelling stories. This role spans content strategy, science translation, digital channels, researcher engagement, & media support. Apply: bit.ly/3PQYa7F

BD²@bipolardiscoveries· May 28

Women’s health is essential to understanding #BipolarDisorder. For International Day of Action for Women’s Health, hear from BD²’s Women’s Health Workgroup on reproductive transitions, research gaps, and more equitable care. 🎬 bit.ly/49VDsu0

BD²@bipolardiscoveries· May 26

BD² Discovery Research Program Director Daniel Pham, PhD, recently spoke at the NCI Center for Cancer Research Fellows and Young Investigators Colloquium. He discussed his career journey and the opportunities for early-career researchers at philanthropic organizations.

Daniel Pham smiling behind the podium at the NCI Research Fellows and Young Investigators Colloquium.

BD²@bipolardiscoveries· May 21

Progress in mental health research requires better data, deeper understanding, and care shaped by lived experience. Through the Integrated Network, BD² participants are helping advance patient-centered bipolar disorder care. 🔗 Explore our first dataset bit.ly/4tF5f9N #MentalHealthAwarenessMonth

Quote from a researcher at McMaster University reading "By integrating biological, psychological, and social data, we can move beyond trial-and-error care toward a more precise, patient-centered approach." Displayed on a green textured background.

Quote from a researcher at UCLA reading "Grounding symptoms in biology can counter stigma and help patients better understand — and engage in — their care." Displayed on a green textured background.

Quote from a researcher at UCLA reading "Participants are grateful that a project like BD² exists. Many have mentioned that they feel there is still so much to learn about bipolar disorder, and they hope that this research can help lead the way." Displayed on a green textured background.

Quote from a researcher at University of Michigan reading "A few themes have emerged across participants: resilience, the ability to find meaning in their disorder, and deep gratitude that this study exists. Many share our goal of improving the lives of others living with bipolar disorder." Displayed on a green textured background.

BD²@bipolardiscoveries· May 12

Charles Lynch, PhD, and the BD² Discovery team at @weillcornell.bsky.social, in collaboration with @stanfordmedicine.bsky.social, are leveraging individualized brain imaging to map circuits and inform targeted interventions in #bipolardisorder.

BD²@bipolardiscoveries· May 7

We’re growing our team 🌱 Hiring a PhD/postdoc-level intern to support program ops and research coordination across a global bipolar disorder research network. From meeting prep and grant tracking to decks and newsletters, you’ll turn complex science into clear, actionable work. 🔗: bit.ly/4tlBaLO

BD²@bipolardiscoveries· May 6

📊 We’re sharing the largest multi‑modal psychiatric dataset—built across 6 sites with shared standards, aligned protocols & rigorous QA. The result: trusted, accessible data ready to drive new discoveries and collaborations. 🔗 www.bipolardiscoveries.org/our-work/dat...

BD²@bipolardiscoveries· Apr 30

🔍 What’s driving momentum in bipolar disorder research? At BD²’s poster session, researchers shared how studying bipolar disorder more deeply and collaboratively helps link science with real patient experience. That connection is what’s accelerating discovery. 🎥

BD²@bipolardiscoveries· Apr 28

“It’s not just about investing in bipolar research—it’s about improving care and building a community.” — @dr-altimusprime.bsky.social, PhD BD² is expanding access to data to spark ideas and drive impact for people with bipolar disorder. 📺: bit.ly/4cJpyMk

BD²@bipolardiscoveries· Apr 24

🧠 @foxmdphd.bsky.social and his BD² Discovery Research team at @mgbresearch.bsky.social are mapping brain circuits tied to specific bipolar symptoms—unlocking targeted neuromodulation treatments rather than one-size-fits-all approaches.

BD²@bipolardiscoveries· Apr 23

📊"The public release of data means more investigators, clinicians, and individuals with lived experience can start answering these questions. The time is now." - Mark Frye, MD, BD² SSC member and Integrated Network co-chair, on BD²’s first data release 🧠Learn more about the release: bit.ly/4vLaaHO

BD²@bipolardiscoveries· Apr 21

Our first public data release is live, shaped by the lived experiences of our participants. Years in the making, this dataset lays the groundwork to accelerate discovery, advance precision medicine, and support people with bipolar disorder in thriving: now and in the future. 🔗 bit.ly/4tF5f9N

Yellow graphic with a white outlined illustration of five people in the top right corner. White text reads "615 participants included in de-identified data."

BD²@bipolardiscoveries· Apr 17

📢 We're excited to welcome Erin Ross, BD²’s Director of Operations. Erin brings deep experience in science philanthropy and operations, and she will help align strategy and execution to advance bipolar disorder research. Welcome, Erin!

BD²@bipolardiscoveries· Apr 15

🧬 What’s powering the next wave of bipolar disorder research? Investigators across the BD² network are exploring bioenergetics, organoids, proteomics, and new shared data—working toward a future where everyone with bipolar disorder can thrive. Hear from a few of them at our latest Poster Session. 🎥

BD²@bipolardiscoveries· Apr 7

When clinicians and researchers work together toward the goal of improving lives for those with #bipolardisorder, collaboration shifts how research progresses. Hear from Tracy Young-Pearse, PhD, on BD²'s integrated approach in the latest #InvestigatorInsights. 🧠

BD²@bipolardiscoveries· Apr 3

Bipolar disorder research has long been slowed by fragmented data. BD²’s first Integrated Network data release helps change that, bringing together rich, longitudinal data to support more connected, collaborative discovery. 🔗See what more connected data unlocks: bit.ly/4tF5f9N

Graphic of rainbow data points over a black background with the white text reading "BD² Integrated Network Data Release" across the center.

BD²@bipolardiscoveries· Mar 30

On #WorldBipolarDay, we've released the largest integrated dataset in psychiatry and created a new cornerstone for #bipolar research. Clinical, imaging, wearable, and biological data—combined longitudinally and standardized across sites. 🧠📈 🧪 Learn more: www.bipolardiscoveries.org/our-work/dat...

BD²@bipolardiscoveries· Mar 19

🧠 Women’s mental health research has historically been underfunded and underprioritized, with much of women’s health research focused on obstetrics and gynecology. This #WomensHistoryMonth, BD²’s Women’s Health Workgroup is helping close gaps by studying how bipolar disorder can differ in women.

BD²@bipolardiscoveries· Mar 17

🧠🔬Last week, 150 members of the BD² network convened for our 3rd annual Investigators Meeting. From genetics and brain circuits to whole-body health, we are uniting science and community to turn breakthroughs into improved care for people living with bipolar disorder.

Members of the BD² network standing outside with the ocean in the background, smiling and wearing colorful BD² branded hats during the Investigators Meeting.

BD²@bipolardiscoveries· Mar 12

What’s next in bipolar disorder research, and how do we get discoveries into care faster? We’re launching #InvestigatorInsights, a new series featuring researchers and investigators across the BD² Network. Hear from Lisa Eyler, PhD, about how BD² is moving insights into action. 🧠

BD²@bipolardiscoveries· Mar 10

Sex and gender differences in bipolar disorder have only been more clearly defined in the past two decades. This #WomensHistoryMonth, listen to Aysegul Ozerdem, MD, PhD share a snapshot of how research in women’s mental health, including perinatal bipolar disorder, has evolved. 👩‍🔬

BD²@bipolardiscoveries· Feb 18

🎥 Last month, Laureate Institute for Brain Research welcomed BD² SSC member and Integrated Network co-chair Mark Frye, MD for a lecture on precision medicine in #BipolarDisorder and depression.