Evidence-based Neonatology
@ebneo
The international society disseminating neonatal clinical research evidence: #ebneoalerts curate, #ebneoreviews appraise, #ebneopolls survey.
Similar to the HEAL trial, the PAEAN trial in @jamapediatrics.com found no difference in EPO + TH vs TH alone in the reduction of death or disability in newborns with HIE. jamanetwork.com/journals/jamap… #EBNEOalerts #neoEBM #neoSky
Kakkilaya et al. conducted a multicenter pilot randomized clinical trial comparing Delivery Room Less-Invasive Surfactant Administration (DR-LISA) with Early Rescue NICU-LISA in extremely preterm infants (22–25 weeks GA). buff.ly/XLvXdbf #EBNeoAlerts #NeoEBM #NeoSky
Early registration for #CEPAS2026 ends July 31st! Register now for the best rates for members and non-members. buff.ly/Hyw10SS Join @ebneo.bsky.social in Lyon, France from 28-31 October 2026 to see cutting edge neonatal science. #neosky #neoEBM @espr-esn.bsky.social
Faust et al. conducted a cluster-randomized crossover trial comparing Standard Hand Hygiene with Extended Barrier Precautions in NICU infants colonized with third-generation cephalosporins–resistant GN bacteria (3GCR-GNB). buff.ly/blxB0kw #EBNeoAlerts #NeoEBM #NeoSky @jamanetworkopen.com
Nangia et al. conducted an open-label RCT comparing Early Total Enteral Feeding (ETEF) with Conventional Enteral Feeding (CEF) in preterm neonates (27–32 weeks) buff.ly/Kf4aOss #EBNeoAlerts #NeoEBM #neosky
A longitudinal cohort study in @jamapediatrics.com of 7,000+ preterm infants reveals inequities in referrals, evaluations, etc., in the Early Intervention cascade. #ebneoalerts #equity4babies #EBNEOEquityAlerts #neoSky #neoEBM jamanetwork.com/journals/jam...
Deadline is today! Submit your late-breaking abstracts and join us at #CEPAS2026 Lyon, France - October 28-31 buff.ly/iGwgepY @espr-esn.bsky.social #neoSky #neoEBM
5 year follow-up from the PROVIDE trial suggests that additional parenteral AA (1 g/d for 5 days) in ELBW infants does not improve school-age neurocognitive outcomes, and may have potential adverse effects on muscle strength and psychosocial function: buff.ly/cwQ0idh #EBNEOalerts #neoEBM #neosky
3-year interim analysis of the FIREFLEYE next trial demonstrates that aflibercept provides stable control for ROP and comparable safety to laser therapy buff.ly/syYWEED #EBNEOalerts #neoEBM #neosky
Even without bradycardia, oxygen desaturations in very preterm infants are linked to significant cerebral and abdominal hypoxemia. karger.com/neo/article/12… #EBNEOalerts #neoEBM #neosky
Mitra et al. conducted a comparative effectiveness research study to compare the relative effectiveness of different PDA regimens and to compare the clinical outcomes between infants treated with pharmacotherapy and those not treated. buff.ly/JEZiU5U #EBNeoAlerts #NeoEBM #neosky
Martinez et al. conducted a post-hoc exploratory analysis of PLUSS to describe the early respiratory trajectories of infants born <26 weeks’ gestation who received surfactant during their initial NICU admission. buff.ly/Hk697aO #EBNeoAlerts #NeoEBM #neosky
Siefkes et al Vs Mitra et al Which publication posted by @ebneo.bsky.social during May is most likely to impact your practice? IAOTM Vote is now open on our website! ebneo.org/vote #EBNeoPolls #neoSky #neoEBM
Could dexamethasone drops prevent progression of ROP? Swedish population cohort study explores this: aaojournal.org/article/S0161-… #neoEBM #EBNEOalerts #neosky
‼️ Abstract Deadline Extended‼️ Think you missed the deadline yesterday? Don't fret! New deadline April 15th! Get your abstracts submitted and join @EBNEO in Lyon, France for #CEPAS2026 in October. Submit now: buff.ly/ANz6BNi #neosky #neoEBM @espr-esn.bsky.social
Which research shaped neonatology in 2025? 🚀 The EBNEO Impact Article of the Year finalists are live! Help us narrow 8 candidates down to the top 2. Voting is open for 7 days. Make your choice on our website: ebneo.org/impact #neosky #neoEBM #IAOTY #EBNEOpolls
Results of the MoCHA Trial, an NIH NRN funded trial led by Dr. Carlo, published in @jama.com. Does continuing caffeine past discharge in moderately preterm infants shorten length of stay? buff.ly/TrA3w3c #neotwitter #neoEBM #EBNEOalerts
A multicentre randomized non-inferiority trial compares 7 day and 14 day antibiotic courses for uncomplicated neonatal bacterial sepsis in 8 centres in India. buff.ly/dm7j9Hz #neotwitter #neoEBM #EBNEOalerts
David Rub & Elizabeth Foglia review Gallini et al's 2y FU of IN-REC-SURE trial READ:buff.ly/XRPm74P Acta Paediatrica: buff.ly/GelMxpV Incubator: buff.ly/ddRnjpa @99nicu.bsky.social: buff.ly/0M84w72 #neotwitter #EBNEOreviews #ebneoAOM @jama.com
Drs Spahic, Zoubovsky, & Dietz review Faix et al's RCT on TH in neonatal encephalopathy in 33-35 GA READ: buff.ly/ujavt3Z Acta Paediatrica: buff.ly/BGvUgez 99nicu: buff.ly/FTcj81u #neotwitter #EBNEOreviews #ebneoAOM @jama.com
Double-blind, parallel-group randomized trial to assess the effect of norepinephrine vs dopamine as first-line vasoactive agent in neonates with fluid refractory septic shock. #neobluesky #EBNeo #neoEBM #ebneoalerts buff.ly/fZdDFF6
A prospective cohort study enrolling from August 2020 to December 2023 to compare global, regional, and tissue-specific brain volumes in opioid-exposed newborns vs unexposed controls. @jama.com #neobluesky #neoEBM #ebneoalerts
A retrospective study using PRAMS data examines disparities by gestational age in the provision of mother's own milk (MOM) @JAMANetworkOpen buff.ly/YeCPlqH #ebneoalerts #equity4babies #EBNEOEquityAlerts #neobluesky #neoEBM
In this secondary analyses of the ETTNO trial, Franz et al compared the effect of liberal versus restrictive transfusion strategies on intermittent hypoxaemia in ELBW infants. buff.ly/33uSCbK #EBNeoAlerts #NeoEBM #neobluesky
In this randomized controlled trial, DeMauro et al. compared oximetry and clinical outcomes in infants with established BPD who were randomized to higher (≥96%) or lower (90–94%) oxygen saturation target ranges. buff.ly/Lf9KW9N #EBNeoAlerts #NeoEBM #neobluesky
Secondary analysis of the INTACT trial with a 90% follow up rate, evaluating 3 year neurodevelopmental outcomes of infants <32 weeks gestation #neobluesky #ebneoalerts buff.ly/7WKtQEc
Authors developed a data-driven approach that optimizes and standardizes total parenteral nutrition (TPN) using information collected routinely in electronic health records. #nicubluesky #ebneoalerts buff.ly/czyOUM7
A repeated cross-sectional study to estimate the association of change in NICU capacity and neonatal mortality across 246 neonatal intensive care regions based on maternal residence in the United States. JAMA Pediatrics. buff.ly/4hVtmir #EBNEOalerts #neoEBM #neotwitter
A retrospective cohort study examines neurodevelopmental outcomes following fetoscopic myelomeningocele repair in the Journal of Pediatrics buff.ly/4xRSBFv #EBNEOalerts #neoEBM #neobluesky
Changes in trends in PDA management from the Children’s Hospitals Neonatal Consortium #EBNEOalerts #neoEBM #neosky buff.ly/niPAjHH