JAMA Internal Medicine
@jamainternalmed
JAMA Internal Medicine is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications. 🌐 JAMAInternalMed.com
Among acutely ill adults receiving supplemental oxygen, #AutonomousOxygenTitration increased time in normoxemia and decreased time in hypoxemia vs usual care. ja.ma/4z6os7x
Among US adults, 2024–2025 COVID-19 vaccination was associated with a 26% lower risk of COVID-19 ED/UC visits, 35% lower risk of hospitalization, and 41% lower risk of critical illness, with effectiveness declining >6 months post vaccination. ja.ma/4xq8uDJ
💬 Invited Commentary: Autonomous #Oxygen titration in hospitalized patients with acute hypoxemic respiratory failure increased time in normoxemia to 85% vs 63% with usual care and reduced time in hypoxemia to 2.0% vs 3.6%. #MHSRS2026 ja.ma/4bq4hYf
Food-specific IgE panel testing should not be ordered without a clinical history suggestive of IgE-mediated #FoodAllergy. Sensitization alone does not establish diagnosis and may contribute to unnecessary dietary restriction, patient harm and avoidable costs. Learn more: ja.ma/4wxEFAW
A randomized trial in rural #NavajoNation found that a culturally tailored meal program for adults with #HeartFailure reduced hospitalizations or emergency visits and improved food insecurity, quality of life, and blood pressure. ja.ma/45xxsoH
A large cluster randomized trial found no reduction in winter respiratory infection rates among care home residents with the use of portable high-efficiency particulate air filters, compared with standard infection prevention measures. ja.ma/4w4m0Mf
Cluster RCT: On-site #POC-RMPCR in nursing homes did not reduce outbreak size or frequency, but reduced ED transfers and enabled faster #antiviral therapy compared to standard off-site testing. ja.ma/3QJe3O4
An 8-week telehealth mindfulness group medical visit program for adults with #LowBackPain produced modest but sustained improvements in pain intensity and interference at 6 and 12 months vs usual care. ja.ma/3SumjSz
Asynchronous electronic screening prior to #telemedicine visits improved completion and detection rates for unhealthy alcohol use among #veterans in primary care compared with usual staff-administered screening. ja.ma/4vGDRt6
In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4g2acpz
In a randomized trial, higher financial incentives eliminated racial enrollment disparities in a smoking cessation trial, but did not affect gaps by sex, age, or education. ja.ma/4eszegc
Among older adults after #surgery, postoperative #delirium was independently associated with long-term #cognitive decline; rehospitalization did not mediate this association. ja.ma/4vnBefJ
Among US veterans, the 2024-2025 COVID-19 vaccine was associated with a 37.7% lower risk of COVID-19–associated #MACE, with the largest benefit in adults >75 years and those with comorbidities. ja.ma/4aAEWKt
#Arthritis is a leading cause of pain and disability that affects nearly one-third of older US adults, many have inflammatory arthritis. 💡 This Clinical Insights discusses inflammatory arthritis in older adults and offers practical guidance. ja.ma/4a6Cf3p
A community health worker-led, telehealth #diabetes intervention improved HbA1c, cholesterol, and ADA guideline adherence vs usual care in low-income Hispanic adults, addressing 87% of participant concerns via a structured feedback loop. ja.ma/3QuDtyy
Older adults living alone with cognitive impairment are at elevated risk for medication-related harm due to barriers at multiple levels, including lack of reminders, regimen complexity, and unwitnessed adverse effects. ja.ma/4xuvzGn
From JAMA: In this observational study of adults in Stockholm, measured GFR (mGFR) values below 90 mL/min/1.73 m² were associated with progressively higher rates of #mortality, #kidney failure, #heart failure, acute kidney injury, and major #cardiovascular events. ja.ma/4o8zzHY
A financial incentive for hypertension control increased guideline-adherent blood pressure remeasurement but did not improve overall control or health outcomes, highlighting potential unintended harms among patients with borderline hypertension. ja.ma/4e30pgh
A cohort study of >1 million first-time handgun purchasers in California found no increased risk of homicide during the 10-day waiting period compared with matched individuals who had not purchased a handgun. ja.ma/3Re5mLz
This case report describes a woman in her 60s who had an inferior wall myocardial infarction 1 year prior and presented to the emergency department with worsening dyspnea and anasarca for the past 2 months. ja.ma/4dFhug2
In men who had radical prostatectomy for low-grade #ProstateCancer and hypogonadism, 12 weeks of testosterone therapy improved sexual activity, desire, well-being, and physical function without biochemical recurrence. ja.ma/4fEb5nJ
The Inflation Reduction Act’s 2024 drug provisions were associated with a 4.9–percentage point reduction in cost-related medication nonadherence among Medicare beneficiaries; health care–related financial strain was unchanged. lucas_marinacci rkwadhera ja.ma/4f1PLsh
#AnxietyDisorders & symptoms are prevalent & burdensome, & patients are most likely to seek treatment in primary care settings. 📌 This Review details behavioral & pharmacological treatment options for anxiety that are feasible & effective in primary care. ja.ma/4wNeVkB
National analysis linking US board-certified family physician survey responses with Medicare data found that self-reported #burnout was associated with significantly higher rates of physician turnover, including both changing practices & leaving practice. ja.ma/4tXwN9X
#PolycysticOvarySyndrome (#PCOS) is not associated with increased prevalence of benign or pathological ovarian cysts; PCOS remains a syndrome defined by small antral follicles, not cyst formation. ja.ma/4dAgUjC