Andreas Prokop
@poppi62
Using #Drosophila to decipher the cell biology of #neurons during development and #neurodegeneration - #scicomm initiative
Over 15 years of our work consistently supports a cohesive model of neurodegeneration providing useful concepts and directions for future research: "the dependency cycle of local axon homeostasis". Enjoy the read of our completely revamped manuscript: doi.org/10.1101/2025... (PDF fixed)
Sleeping flies with an Alca-Seltzer - ideal for schools: Shoenhard, J Microbiol Biol Educ 0, e00115ff. -- doi.org/10.1128/jmbe... - now linked out on droso4public: droso4public.wordpress.com/resources/#T... Heads-up to @flybase.bsky.social, @the-node.bsky.social & @fly-eds.bsky.social
Fantastic work by the Sanchez-Soriano group establishing causative links from autophagy to ROS to microtubules, eventually resulting in ageing phenotypes of neurons -- Gupta et al., 2026, bioRxiv 2026.05.29.728680ff. -- doi.org/10.64898/202...
Now added to our #Drosophila history collection: droso4public.wordpress.com/history/
This Tuesday I will give my favourite lecture of the year on our Advanced #DevBiol course: The toolbox lecture - The Molecular Biology of the Cell in 1 hour. Each year this slide triggers me to think and refine the rationale - a fun task!
Wonderful to see former group members excel! Congratulations @exdrososcientia.bsky.social! Solis, O., Shaw-McGrath, T., Wade, A. R., Hahn, I. (2025) Steady-state visually evoked potentials as readouts for abnormal GSK3β activity in Drosophila. bioRxiv, 2025.10.24.684304 -- doi.org/10.1101/2025...
Join the 4th Asia Pacific #Drosophila Neurobiology Conference in China: lhs.suat-sz.edu.cn/info/1031/13... @fly-eds.bsky.social @flybase.bsky.social @the-node.bsky.social
Please, stay informed about Ukraine's dreadful situation, being sold by Trump to Russia whilst EU and UK politicians sleepwalk into increased hybrid warfare & massive future expenditure. Follow: Ukraine The Latest: www.telegraph.co.uk/news/2022/03... Battleground: www.podbean.com/podcast-deta...
🧠 Are you passionate about EM, neurons, ageing, neurodegeneration? Then you might be interested in a funded 4-year BBSRC NWD PhD project using vCLEM techniquesat Liverpool with @ianprior.bsky.social, @natsansor.bsky.social and @aliemliv.bsky.social thenode.biologists.com/jobs/fully-f...
If you want to stay informed about what's going on in Ukraine, the weekly "Battleground" podcast on Fridays is excellent (www.podbean.com/podcast-deta...), and the daily "Ukraine: The Latest" outstanding (www.telegraph.co.uk/news/2022/03...)
This paper nicely supports our microtubule-curling-based model in neurons! See an easy read here: doi.org/10.1177/1755... (OA: tinyurl.com/5dysx3d3)
Wow, this paper provides crucial understanding of local translation and processing of transmembrane proteins in axons, one of the big mysteries that have haunted the field for a long time!!!!!!!! Fantastic!!!!!!!! Nguyen et al., 2025, bioRxiv 2025.09.09.674816ff. -- doi.org/10.1101/2025...
Published 7 yrs ag0, I just re-read the editorial & stand to everything I wrote. Given the current political landscape it might be more important than ever to have another careful read to UNDERSTAND THE NEED, HURDLES & STRATEGIES OF #SCICOMM that we can/must take: doi.org/10.1016/j.se...
Over 40 years old and still working! My pocket computer from early student times, programmable in Basic and with printer output.
Hey #Drosophila community: who has already some experience with these new procedures which may also affect normal mail? Please, be so kind to share your knowledge, tips & tricks! @bdsc.bsky.social @fly-eds.bsky.social @flybase.bsky.social - urldefense.com/v3/__https:/...
Dear president@harvard.edu, dear gaudet@mcb.harvard.edu, to learn more about the importance of #Drosophila and crucial role of @flybase.bsky.social, and how it gave rise to at least 9 Nobel laureates in Physiology and Medicine, please see this link: droso4schools.wordpress.com/why-fly/
Finally out: Murray-Cors, S., Owens, M., Liew, Y.-T., Day, M., Cairns, W., Prokop, A. (2025) Impacts of mitochondrial dysfunction on axonal microtubule bundles as a potential mechanism of neurodegeneration. Front Neurosci 19, 1631752 -- doi.org/10.3389/fnin...
Microtubule curling as an efficient readout to uncover fundamental concepts of axonal doi.org/10.1101/2025...
Impacts of mitochondrial dysfunction on axonal microtubule bundles as a potential mechanism of neurodegeneration. Murray-Cors, Owens, Liew, Day, Cairns, Prokop (2025) Front Neurosci 19, in press -- doi.org/10.3389/fnin...
Towards more sustainable research: reducing the environmental impact when working with #Drosophila. Challiner, Saurya., Patel, Raff, Fostier, Prokop, A. (2025) @genetics-gsa.bsky.social, in press -- doi.org/10.1093/gene... - Always happy to discuss and hear your ideas and views!
If you need a simple introduction to axonal cell biology and neurodegeneration for your students, here you go: Shields, Silverdale, Prokop (2024) Understanding the underlying causes of degenerative neural diseases. InnovAiT, 17557380241298477 -- doi.org/10.1177/1755... (OA: tinyurl.com/5dysx3d3)
This title says it all: "This animal is supposed to bring peace to the world - yet is being hated like hardly any other"
