Tim Morris
@timpmorris
Biostatistician working on methodology at Novartis. Simulation studies, non-inferiority, missing data, estimands, covariate adjustment… He/him
Oh no you’re way behind Jack (Can’t believe you made me dig out ttespoof.pdf)
Title for this paper by @annemscheel.bsky.social made me snort. Outstanding. doi.org/10.1002/icd....
I assume lots of you are also receiving this. Somehow the entire message comes off as dripping with contempt. Hooold!
Wonderful bit of ‘added value’ here. New manuscript system seems to use ‘AI’ to suggest my primary affiliation for an accepted paper. That the paper is accepted means I already told the system my affiliation. What a superb list 😆
Thank you to the company who just emailed this reassurance/encouragement 😘
New post on a topic you might have struggled with if you do simulation studies. For a given data-generating mechanism, you might wonder “What is the true value of my estimand?” This post describes four ways to learn it. tpmorris.substack.com/p/learning-t...
Once again: please use your brain when considering “meta-models” for simulation study performance and make the right decision to just not. Using one instantly gets you on my naughty list. open.substack.com/pub/tpmorris...
Hang on… I added "font" to show that this isn’t because it’s ambiguous.
Does this enrage you too? Publishers adding a random page nobody wants at the beginning of a pdf, bigger than the rest of the pages – the ones people actually want to read – messing up the fit-to-width size of pages you do want to read! Just making readers’ lives pointlessly difficult.
New (short) post on hearing criticism of your work. No, I’m not telling you who it was – they will recognise themself! open.substack.com/pub/tpmorris...
The defenders of British Values, having completed their work assaulting police officers, have returned home, leaving London a Dystopian Hellscape once again
I’m just a bit baffled about what you think this is “inferior to”. Writing an subsequent expression in terms of potential outcomes? If so, this should come from the natural-language version, not compete with it. E.g. doi.org/10.1002/sim....
Thanks Cameron! Dean, two key points: 1. It’s the structure in this pic that we all find so useful. 2. The “Intercurrent event strategies” mean interplay with the other four attributes.
Interesting discussion with collaborators about whether it’s acceptable to say anything negative about PPI. They showed a quote that seems like a huge “therefore” lurch! 1/ researchinvolvement.biomedcentral.com/articles/10....
I already think John Baker will be impressed. Can you help my friend out and improve on it?
ISCB46 has been really fun. So much that I’ve barely been on here. Admittedly “bRave little soldieRs” probably shouldn’t have made it into the slides but IN MY DEFENCE I MADE THEM WITH QUARTO 😇
Post just up: Is multiple imputation making up information? tldr: no. Includes a cheeky simulation study to demonstrate the point. open.substack.com/pub/tpmorris...
I’m glad you brought up sons. All the good photos I get are with my son, which you can’t use as a headshot. Also true of sunglasses.
New post: “Marginal” and “conditional” are relative descriptions of an estimand