PEARL trial (114 adults, 48 wks): rapamycin missed its main goal (visceral fat). But women on the 10mg dose saw real gains in lean muscle & less pain — not seen in men 💊 Honest science: one miss, one real signal. www.aging-us.com/article/2062... #GeroScience #Rapamycin #AgingResearch

The most-cited framework in aging research: 12 "hallmarks of aging," from genomic instability to cellular senescence to chronic inflammation — each a real target for intervention. doi.org/10.1016/j.ce... #HallmarksOfAging #GeroScience #Longevity

CALERIE-2, the first controlled human CR trial: cutting calories by just 14% over 2 years regrew part of the thymus & boosted fresh T cell output 🧬 Researchers found a gene (PLA2G7) that may explain why. www.sciencedaily.com/releases/202... #GeroScience #ImmuneAging #AgingResearch

Research to Impact: Building Science Communications is a free program designed for emerging investigators in aging biology, offered by @nathanshockcenters.org and @afar.org. 📅 Deadline to apply: August 7 nathanshockcenters.org/nsc-research-to-impact-building-science-communications-program

New Nature Aging framework mapped 2,358 aging genes onto the human protein network, screened 6,442 existing drugs, and found 370 that could affect aging hallmarks — 21 pro-longevity, 23 age-accelerating. A systematic map, not a cure. www.nature.com/articles/s43... #GeroScience #Longevity

New Nature Aging study: it's not just your epigenetic age that predicts survival — it's how fast it's changing. Accelerating biological age = higher mortality risk, regardless of starting point 🧬⏱️ #EpigeneticClock #Longevity #AgingResearch

25,000+ women tracked 25 years: closely following a Mediterranean diet = 23% lower risk of dying from any cause 🫒 (JAMA Network Open) www.health.harvard.edu/heart-health... #MediterraneanDiet #Longevity #Nutrition

Why does fasting extend lifespan? A 2026 Nature Comm study found it's about how efficiently cells shut off lipid-burning after a fast — get that right, lifespan jumps 60%+ in worms 🔬 doi.org/10.1038/s414... #Longevity #Fasting #AgingResearch

Landmark study of 9,000+ people: as we age, our gut microbiomes become more unique to us — and the people with the MOST distinctive microbiomes lived longer & healthier 🦠 pubmed.ncbi.nlm.nih.gov/33619379/ #GutHealth #Microbiome #Longevity

2026 pilot study: 13 weeks of spermidine improved vaccine antibody responses in adults 65+ by reversing signs of immune cell aging 💉 Especially helped people who initially responded poorly. onlinelibrary.wiley.com/doi/full/10.... #ImmuneHealth #HealthyAging #GeroScience

New Nature Aging study: it's not just your epigenetic age that predicts survival — it's how fast it's changing over time. Accelerating biological age = higher mortality risk, regardless of starting point 🧬⏱️ www.nature.com/articles/s43... #EpigeneticClock #BiologicalAge #Longevity

5,400+ women 63+, tracked for years: stronger grip = 15% lower death risk per 7kg increase. Faster chair stands = 9% lower risk per 6 sec improvement. Independent of activity level 💪 www.health.harvard.edu/bones-and-jo... #Longevity #StrengthTraining #HealthyAging #MuscleMatters

Middle-aged people with long-lived parents develop heart/metabolic disease ~13 yrs later than partners without that genetic edge, per new Leiden research 🧬 Longevity runs in families — science is figuring out why. www.sciencedaily.com/releases/202... #Longevity #AgingResearch #Genetics

NAD+ = the molecule behind energy, DNA repair & cell signaling. Levels drop as we age — and it's one of the top longevity trends physicians are watching in 2026 ⚡ honehealth.com/edge/longevi... #NAD #CellularHealth #LongevityScience #HealthyAging #Biohacking #AgingWell #Metabolism

Independence isn't just a 4th of July thing — it's a longevity goal 🇺🇸 The freedom to move, think clearly & thrive at 70, 80, 90+ is what healthy aging research is fighting for. Happy 4th from AGE! #HappyFourthOfJuly #HealthyAging #Longevity #IndependenceDay #AmericanAgingAssociation

Xiamen University: declining Menin in the hypothalamus triggers inflammation, memory loss and bone loss simultaneously. Restoring it reversed those effects in 30 days. A simple amino acid called D-serine restored memory on its own. Published in PLOS Biology. 🔗 www.sciencedaily.com/releases/202...

$225 million invested in aging research. 4,539 researchers funded. Yet the US has fewer than 7,500 geriatricians — and needs 30,000 by 2030. AGE stands alongside organizations like #AFAR in building that pipeline. 🔗 www.afar.org/grant-programs #AgingResearch #Geroscience

The longevity field just shifted its core question. 🔬 Not "what is broken in aging?" but "how do biological systems lose coordination with each other over time?" The 2026 World Congress on Targeting Longevity: aging is a systems problem. Not a single fix. 🔗 www.eurekalert.org/news-release...

A tropical butterfly barely ages — and lives 25x longer than its relatives. Heliconius butterflies show little to no physical decline even in old age. Even without pollen, they outlive relatives by weeks. Nature's blueprint for longevity exists, read it here! www.nature.com/articles/s41...

Glucosamine is one of the most popular joint supplements in the world. New research links it to 25% faster progression to Alzheimer's disease. 🔬 Supplements need the same scientific scrutiny as any intervention. Especially for aging adults. 🔗 www.sciencedaily.com/releases/202... #Geroscience

Nearly 50% of adults 65+ didn't decline with age — they actually got better. New Yale study: cognitive AND physical improvements measured in nearly half of older adults over a decade of data. Aging isn't just decline. The science proves it. bit.ly/4b2wW58 #HealthyAging

2,390 researchers from 89 countries agree: longevity science has crossed the clinical threshold. 🌍 The 2026 GESDA Breakthrough Radar says the debate is over. The question now is policy — not possibility. 🔗 www.gesda.global/radar-spotli... #Geroscience #Longevity #AGE2026

Scientists reversed cellular aging in just 2 days. Leibniz Institute on Aging found that declining phosphatidylcholine fragments mitochondria — a core driver of cellular aging. Restoring it via diet reversed the damage in 2 days. 🔗 www.sciencedaily.com/releases/202... #Geroscience #AgingScience

Did you know your brain can keep forming new connections well into your 80s and beyond? Neuroplasticity doesn't have an expiration date. Research shows that mentally stimulating activities actively support cognitive resilience as we age. #AgingScience #Geroscience #BrainHealth

1 in 4 Americans will be over 65 by 2060. That's not a distant projection. That's 27 years away — and the science of aging needs to catch up fast. AGE funds the researchers targeting that root cause. Not just the symptoms. #AgingResearch #HealthyAging #Geroscience #Longevity #AGE2026

Senolytics don't just delay aging — they may turn back your biological clock. Senolytic compounds reduced epigenetic age in human blood samples. Senescent cells drive epigenetic drift. Remove them — the clock partially resets. 📄 Free: www.ncbi.nlm.nih.gov/pmc/articles...

AGE 2026 is a wrap. 4 days. 10 sessions. 3 award lectures. 225+ posters. Trainee programs. Longevity biotech. The full breadth of geroscience. Thank you to every speaker, presenter, trainee, sponsor, and attendee. This community delivered. See you at AGE 2027. 🙌 #AGE2026 #Geroscience #AGE2027

Day 3 of #AGE2026 — done. ✅ Chronobiology & Aging ✅ NIA Funding for ESIs ✅ Trainee Poster Pitches II ✅ Mark Smith Award ✅ Ovarian Decline & Female Aging ✅ Interorgan Communication ✅ 108 Posters ✅ Trainee Data Blitz Tomorrow — Final Day One more day. Make it count. #Geroscience #AGE2026 #Day3

Day 2 of #AGE2026 — done. 🔬 ✅ Opening Remarks · Dr. Adam Salmon ✅ Early Life Effects on Aging ✅ Environmental Toxins & Aging ✅ Denham Harman Award ✅ AFAR Cristofalo ✅ Immune Aging ✅ Longevity Biotech ✅ 117 Posters · Trainee Mixer Follow live → americanagingassociation.org #Geroscience #AGE2026

Slots open for postdoctoral fellows — UT San Antonio Biology of Aging T32 Training Program. · Clinical studies · Grantsmanship training US Citizens/PR only. 1 year renewable. 📩 salmona@uthscsa.edu 🔗 age.memberclicks.net/assets/image... #T32 #PostDoc #Geroscience #AgingResearch #BiologyOfAging