CU Department of Biomedical Informatics
@cubiomedinfo
DBMI connects basic science and medicine with clinical and translational scientists at the #CUAnschutz Medical Campus
A study by a team including @cuanschutz.bsky.social researcher Tell Bennett, MD, evaluated Acute Kidney Injury (AKI) risk prediction models in pediatric critical care. The study found that incorporating multi-center data improved model prediction performance ➡️ https://cudbmi.info/aki-model-1
A new study published in @gigascience.bsky.social, led by researchers at @cuanschutz.bsky.social, introduces KG-Microbe: a knowledge graph (KG) framework that harmonizes and standardizes microbial data to support microbiome research. Learn more here ➡️ https://cudbmi.info/kg-microbe-1
What a fantastic week at #ISMB2026 in Washington, D.C. Our DBMI team from @cuanschutz.bsky.social was well represented, with researchers delivering talks, showcasing posters and facilitating panels throughout the week. Thanks to everyone who connected, collaborated and shared their work.
Congratulations to Aishwarya Mandava, researcher in the Krishnan Lab at @cuanschutz.bsky.social, for winning the TransMed COSI Best Poster Award at #ISMB2026 🎉
Final day of #ISMB2026 DBMI has oral presentations from Samantha Lopez Alvarez plus poster presentations from Kewalin Samart, Abhirupa Ghosh and Evan Brenner. Plus visit our booth from 10:00 a.m.–4:40 p.m. Get the details here: https://cudbmi.info/ismb-2026-1
Wednesday at #ISMB2026 Don't miss oral presentations from Emma Lathouwers, Lucas Gillenwater, Evan Brenner, Katerina Terwelp, and Akshay Kumar Avvaru. Plus, visit DBMI’s booth from 10 a.m.–4:40 p.m. Get the details here: https://cudbmi.info/ismb-2026-1
DBMI has a full Tuesday at #ISMB2026 Visit our booth from 10:00 a.m.–4:40 p.m., explore posters from Lucas Gillenwater and Abhirupa Ghosh, and attend Mónica Muñoz Torres’ open science panel. Get the details here: https://cudbmi.info/ismb-2026-1
Day 2 at #ISMB2026 DBMI’s booth is open today from 10:00 a.m.–4:40 p.m. in the Columbia Ballroom. Come meet our researchers and learn more about biomedical informatics at CU Anschutz. Check out our booth schedule and ISMB Research Showcase here: https://cudbmi.info/ismb-2026-1
We're kicking off #ISMB2026 in Washington, D.C. Stop by our booth in the Columbia Ballroom today from 4:00–9:00 p.m. to connect with our researchers and learn more about our department. Check out our presenter schedule, booth schedule and ISMB Research Showcase here: https://cudbmi.info/ismb-2026-1
Can AI say "I don't know"? Although Large Language Models (LLMs) have come a long way, they still struggle with declaring uncertainty—a vital task in clinical settings. Read more in the perspective led by @cuanschutz.bsky.social researcher Andrea Sikora, PharmD➡️ https://cudbmi.info/can-ai-say-idk-1
The medicalcoder R package supports running comorbidity algorithms on datasets—even those with ICD-9 and ICD-10 codes. Today, developer @peteredewitt.bsky.social is presenting medicalcoder at the virtual R/Medicine 2026 conference at 2:06 p.m. ET. Learn more here➡️ https://cudbmi.info/medcoder-1
Emily Meyer, PhD, and James Mitchell, PhD will be presenting a poster at NORDP. The Facilities and Resources Generator, highlights a software tool that streamlines how facilities and resources sections are created for grant proposals. 🗓️ April 28, 2026 | 12:45–2:00 PM ET 📍 Exhibit Hall, JW Marriott
At CU Anschutz, our researchers are unlocking biological insights from incomplete datasets by providing guidelines to achieve near scRNA-seq accuracy in bulk deconvolution, enabling deeper insight into cell types and states within complex tissues ➡️ https://cudbmi.info/rna-guidelines-1
Pseudomonas aeruginosa is a pathogen that often dominates infections in vulnerable tissues or hosts. CU Anschutz researchers found resistance only in clinical strains, identifying how antibiotic pressure can increase its threat and complicate treatment ➡️ https://cudbmi.info/pseudomonas-aeruginosa-1
Pediatric blood pressure isn't the simple 120/80 'healthy' ceiling we learn for adults—it's a function of age, sex and more. Led by @peteredewitt.bsky.social researchers @@cuanschutz.bsky.social developed pedbp: a tool for pediatric blood pressure percentiles. Learn more➡️ https://cudbmi.info/pedbp1
Resarchers @cuanschutz.bsky.social developed MUSE, one of the first multi-LLM uncertainty algorithms grounded in information-theoretic principles. Instead of relying on a single model’s output, MUSE leverages a subset of models. Learn more➡️ https://cudbmi.info/muse1
Using a familiar correlational coefficient like Spearman’s or Pearson’s on molecular data may miss some complex patterns that exist. To overcome this, researchers at @cuanschutz.bsky.social including @miltondp.bsky.social developed CCC—a new statistical framework ➡️ https://cudbmi.info/ccc-1
Sparse data and lack of reliable models are challenges in estimating biological systems. Researchers at @cuanschutz.bsky.social introduced a multi‑objective data assimilation framework for complex biological systems➡️ https://cudbmi.info/multiobjective-optimization1
Clinicians have a lot to consider for patient medications. LLMs could support medication management, but medications pose unique challenges for these LLMs. @cuanschutz.bsky.social researchers developed a benchmark suite to evaluate these implementations: https://cudbmi.info/rx-llm-1
Researchers developed a model that leverages EHRs to predict which children with severe TBI will go on to receive ICP monitoring. The findings can inform the design of a clinical decision support tool. Learn more ➡️ https://cudbmi.info/icp_monitor_tbi1
Researchers at @cuanschutz.bsky.social are examining methods to overcome challenges in personalized oncology. In a recent perspective, the researchers explore hybrid models (mechanistic + ML) to improve model fits and potentially prediction. Learn more➡️ https://cudbmi.info/personal-oncology-JAMIA-1
You may not know what NLP is, but it's very prevalent in our lives. @compbiologist.bsky.social, PhD, associate professor @cuanschutz.bsky.social explains NLP and how he uses it to help biomedical data be reused for new discoveries. Learn more➡️ https://cudbmi.info/natural-language-processing-1
Interdisciplinary research is challenging but vital for innovation and better patient outcomes. The latest JAMIA issue highlights this approach, with @cuanschutz.bsky.social researcher David Albers, PhD, as associate guest editor. Read more➡️ https://academic.oup.com/jamia/article/33/1/1/8408480
AI is rapidly reshaping clinical care. CU Anschutz researcher Yanjun Gao, PhD, explores how we can ensure these AI tools are safe, transparent and aligned with human needs. Learn more here ➡️ https://cudbmi.info/health-ai-2026-1
phoenix supports researchers in implementing Phoenix & Phoenix-8 pediatric sepsis scoring—providing more reproducible research and findings that translate into better care over time. Learn more about the tool developed by researchers @cuanschutz.bsky.social➡️ https://cudbmi.info/phoenix-package-1
Computational methods are improving how we translate discoveries from model organisms to humans. Researchers including @compbiologist.bsky.social propose agnology: “agnostic” to evolutionary history, driven by data. Learn more➡️ https://cudbmi.info/computational-methods-human-disease-1
Meet the Claw Lab, where researchers partner with the community to build a stronger foundation for ethical, collaborative and adaptive personalized medicine ➡️ https://cudbmi.info/claw-lab-1
Every breakthrough in 2025, from new ICU guidelines to building one of the most complete human genome maps, reflects the power of working together to improve lives. Discover the stories behind the impact ➡️ https://cudbmi.info/top-stories-2025-1
Researchers at CU Anschutz created an automated system that continuously collects ventilator waveforms and links them with patient health records. Explore what this means for ICU care ➡️ https://cudbmi.info/data-pipeline-ventilator-waveforms-1
📢 CCPM Seminar Alert! Join us Tuesday, Dec. 9 at noon for an insightful session with Katrina Claw, PhD, and Randi Johnson, PhD, MPH. ➡️ Details here: https://cudbmi.info/ccpm-seminar-2025-1