PwMS face barriers to specialized care, but short-term intensive programs may offer a viable solution. Data show that, by providing condensed education on symptom management and lifestyle tools, these programs significantly improve outcomes compared to traditional care. www.doi.org/10.7224/1537...

Why do half-lives matter in MS DMTs? Ofatumumab’s ~16-day half-life can lead to faster B-cell repopulation than IV options. Case study reports significant relapse after just a 4-month gap. doi.org/10.7224/1537... #MultipleSclerosis #ofatumumab

Aging with MS isn't all downhill, data suggest. In adults 55+ with MS, physical limitations increased over an average 8.3 years of follow-up, but psychosocial well-being held steady or even improved. Study by the NY State MS Consortium. doi.org/10.7224/1537... #aging #MultipleSclerosis #PROMs

Feeling capable and making movement part of your identity are keys to staying active. In this study, when physical activity felt personally relevant and not generic, participants were more likely to continue. doi.org/10.7224/1537... #MultipleSclerosis #exercise #PhysicalActivity #choice

MS rehab should last longer than a few months. Study data suggest that while gains start early, the second year of a program can be where the most significant improvements in performance happen, especially for those with higher disability scores. doi.org/10.7224/1537... #MultipleSclerosis #rehab

Older adults with MS face a compounding effect of aging and disability. Study suggests addressing social determinants of health, structural ageism and ableism, and comorbidities can improve quality of life and care satisfaction. A multidisciplinary model is a priority. www.doi.org/10.7224/1537...

2025 3rd place: Webbed mitochondria (James Costanzo). medschool.vanderbilt.edu/basic-scienc... #NeuroArtFriday #FluorescenceFriday

Manage the modifiable in MS: We can't change disease duration, but we can treat hypertension and obesity. Even if the benefit doesn't show up on an MRI, the long-term data suggests it is one of the best tools to protect quality of life. doi.org/10.7224/1537... #MultipleSclerosis #comorbidity

Study: MS can compromise walking automaticity, so PwMS rely more on conscious cognitive resources. Interventions should real-world stability and include tasks that require shifting attention back and forth between the movement and the environment. doi.org/10.7224/1537... #MultipleSclerosis #walking

The Emerging Role of Optogenetics in Multiple Sclerosis Research: "Possible future applications...include the induction of oligodendrocyte proliferation, myelin synthesis, enhancing the repair of demyelinating processes, and modulating the severity of MS symptoms." doi.org/10.7224/1537...

"Qigong and tai chi...are multicomponent forms of exercise, which means that they address not only physical health, but also can address psychological health and cognitive health...these types of movement also integrate relaxation and help with cognition." www.ijmsc.org/view/ijmsc-a... #TaiChi #MS

"Virtual reality...may provide psychological advantages to traditional rehabilitation services...the CAREN system may be associated with a positive effect on patients’ mood and subsequent QOL while also contributing to effective physical and cognitive rehabilitation." doi.org/10.7224/1537...

"A novel battery of self-administered, smartphone application–based neuroperformance tests would allow more frequent, remote assessments of motor and cognitive function in people with multiple sclerosis." www.doi.org/10.7224/1537... #smartphone #neuroperformance #remote #MultipleSclerosis

"We present 4 models of MS health care delivery and discuss how integrating pharmacy services into an MS multidisciplinary team can potentially increase the efficiency and quality of health care delivery." doi.org/10.7224/1537... #pharmacy #pharmacist #MultipleSclerosis #ComprehensiveCare

"[There’s] not one prescribed pathway [for] having a pharmacist or a pharmacy team integrated into comprehensive MS care. It has to work for the type of environment and patients and the organization that you are functioning in. There has to be flexibility…" www.ijmsc.org/view/ijmsc-a...

"This study examined the difference in arterial stiffness between people with MS and controls and whether the difference was accounted for by anxiety, depression, and walking endurance, variables not usually included in other studies of arterial stiffness in MS." www.doi.org/10.7224/1537...

Narrative review "discusses how comorbid disease and polypharmacy affect people with MS, strategies to mitigate these negative risks, as well as areas where evidence is lacking and further study is needed to inform optimal treatment strategies for older adults with MS." www.doi.org/10.7224/1537...

#NeuroArtFriday #admire #writer #advice

Restless Legs Syndrome is common in people with MS, affecting ~26%. Symptoms are often worst when falling asleep, but RLS experienced during active daytime hours is also strongly linked to brain fog like slower processing and visual memory challenges. doi.org/10.7224/1537... #MultipleSclerosis #RLS

Men with MS feel pressure to maintain emotional control which is linked to poorer health-promoting behaviors; those who cope with positive reappraisal focused more on self-care. Socialized gender roles shape MS management and help-seeking behaviors. doi.org/10.7224/1537... #MultipleSclerosis #gender

"The goal...is...a targeted review of recent literature that focuses on specific end points related to #MS #progression. We then discuss available evidence on key limitations of the EDSS...and highlight some measures that may assist in improving [its] sensitivity...." doi.org/10.7224/1537...

"This review discusses the future of optogenetics as a potential treatment for MS. This innovative technology may offer an improved approach to managing [MS], offering refined control over drug delivery, remyelination, and gene therapy." doi.org/10.7224/1537... #optogenetics #MultipleSclerosis

Rehabilitation nursing is complex involving coordinating care, providing emotional support, and managing situational instability. Research is currently moving toward the development of research-supported nursing consultations to ensure continuous support. doi.org/10.7224/1537... #MultipleSclerosis

Wearable tracker data show that people with MS remain largely sedentary even during intensive rehab periods. To reach the activity levels needed for long-term health benefits, clinicians should provide specific, tailored advice. doi.org/10.7224/1537... #MultipleSclerosis #PhysicalActivity

What kind of journal is IJMSC? What kinds of research do we publish? Who is our audience? Hear the details from Editor in Chief Francois Bethoux, MD. Explore more: www.ijmsc.org/research

MS affects women at a 3:1 ratio, often diagnosed during peak reproductive years. This study finds OBGYN clinicians lack confidence in managing MS-specific issues like contraception for patients with immobility or DMT safety during pregnancy. www.doi.org/10.7224/1537... #MultipleSclerosis #OBGYN

"My goal is to treat storytelling as a form of care work: collaborative, non-linear, to meet access needs, and grounded in an individual's own language and representation." ~Sal Marx sps.columbia.edu/news/artists... #NeuroArtFriday #care #NarrativeMedicine #voice

Remote 5XSit-to-Stand test for people with MS. Reliable: ICC of 1.00 compared to concurrent in-person testing Clinically Valid: Moderate-large associations with hip and knee isometric strength Safe & Practical: Individuals with PDDS scores 0–6; no special equipment. doi.org/10.7224/1537...

New scoping review finds factors like thoracic kyphosis (posture), fatigue, and sleep quality are linked to breathing efficiency in MS. Physical therapy and multidisciplinary care can help optimize general health outcomes. doi.org/10.7224/1537... #MultipleSclerosis #breathe

#CMSC2026 Jemima Akinsanya: Without diverse data, clinicians lack critical information on potential differences in drug metabolism, safety profiles, and immune mechanisms across different patient populations. #MultipleSclerosis