Intensive Care Medicine Journal
@intenscaremed
Intensive Care Medicine serves as the premier publication platform facilitating the communication and exchange of cutting-edge research and ideas within the field of intensive care medicine on a comprehensive scale. This platform is designed for profession
Letters to the editor have been retracted after claimed undeclared LLM use, while the retraction notices lacked detailed evidence. zurl.co/JgaBL
Prehospital airway and ventilatory management requires timely intubation, physiology optimization, structured rescue pathways and cautious use of non-invasive respiratory support. zurl.co/r2jb9
Ventilator-associated pneumonia management is moving toward greater precision through microbiome, immune, molecular diagnostic, prevention, and antibiotic optimization strategies. zurl.co/48Rgw
In patients with sepsis or septic shock, mNGS added to routine microbiological diagnostics did not improve the DOOR/RADAR score but favored several secondary outcomes. zurl.co/kGJgK
Electrical impedance tomography provides real-time regional assessment of lung aeration, ventilation and perfusion in ARDS, but clinical translation remains incomplete. zurl.co/09eh9
#VisualAbstract Acute respiratory distress syndrome prevention has substantially succeeded for iatrogenic phenotypes, while noniatrogenic causes remain challenging. zurl.co/cJaiu
Hypercalcemia in ICU patients disrupts calcium homeostasis and may cause kidney, cardiovascular, neurological, and digestive complications. zurl.co/1xNn0
The HLH-Risk-Calculator predicted initial disease severity and time-point specific mortality in adult secondary hemophagocytic lymphohistiocytosis patients. zurl.co/Eiqlr
ICU family support outcomes require cautious interpretation when cluster randomization includes only a limited number of ICUs. zurl.co/NqkZG
#VisualAbstract Patient Blood Management in the ICU includes anemia management, reduced diagnostic blood loss, restrictive transfusion strategies and individualized blood product use. zurl.co/4RPA8
BMI alone has limited individual prognostic value in critical illness, while frailty and central adiposity phenotypes may refine ICU risk stratification. zurl.co/o7UPU
Obesity alone should not preclude ECMO access, particularly VV-ECMO, but care requires anticipation of physiological, technical and organisational challenges. zurl.co/MxDhl
Probabilistic ARDS subphenotyping captures risk variation within inflammatory groups and changing trajectories over time. zurl.co/u9f2f
#VisualAbstract Updated recommendations define clinical use of point-of-care lung ultrasound as a standalone bedside tool, covering signs, techniques, monitoring, prognosis and adult applications. zurl.co/vqE8G
In high-risk hypertensive patients undergoing major elective abdominal surgery, targeting an intraoperative MAP of at least 80 mmHg reduced major organ dysfunction compared with at least 65 mmHg. zurl.co/NNa4m
In acute respiratory distress syndrome, PEEP effects reflect recruitability, overdistension risk, airway closure and hemodynamic tolerance. zurl.co/AytQ6
Vitamin C may worsen organ dysfunction after out-of-hospital cardiac arrest, with higher-dose treatment linked to unfavorable outcomes in intensive care. zurl.co/ehcOJ
Greater ABCDE bundle compliance was linked to modest 12-month improvements in daily functioning and health-related quality of life, but not to cognition, basic activities, post-traumatic stress symptoms or survival. zurl.co/wKAmm
Older ICU patients face heterogeneous aging-related vulnerability, while guidance remains limited by scarce high-quality evidence. zurl.co/P6Zsc
#VisualAbstract Nutrition support in critically ill patients requires a cautious, phase-adapted approach, with low-calorie and low-protein strategies considered during acute illness and individualised support during recovery. zurl.co/tFprA
Online and virtual reality intensive care training generated median emissions of 43 kg CO₂ per participant, compared with 429 kg for modelled in-person attendance in Brussels. zurl.co/ZUOYY
Acute brain injury during extracorporeal life support is common and is linked to mortality and long-term disability. zurl.co/O6ACW
PEEP in ARDS can improve oxygenation while reshaping venous return, with systemic venous congestion and organ dysfunction varying by lung recruitability and pressure transmission. zurl.co/RQBwN
#VisualAbstract Online and virtual reality training produced significantly lower CO2 emissions than hypothetical in-person intensive care training. zurl.co/9UZnt
Prophylactic noninvasive ventilation with high-flow nasal oxygen reduced day 7 reintubation in high-risk patients without hypercapnia after extubation. zurl.co/1ZHmm
Early intravenous vitamin C did not reduce organ dysfunction at 96 hours after shockable out-of-hospital cardiac arrest, and the 10 g dose worsened organ function outcomes. zurl.co/2ruey