Joao Pedro Magalhaes
@jpsenescence
Scientist decoding the aging genome, professor, geek, entrepreneur, speaker, writer, keen footballer.
Novo Nordisk's clinical trial for Ziltivekimab, an antibody targeting pro-inflammatory cytokine IL-6, failed 👀 Interestingly, both IL-6 and hsCRP fell with treatment, suggesting an anti-inflammatory effect, yet this did not translate into fewer cardiovascular events.
I'm delighted to be speaking at the Longevity Summit Portugal 2026 on 18 September in my hometown of Porto. Looking forward to discussing the latest advances in longevity science and meeting colleagues from across the scientific and medical communities. lp.centroinovacaomedica.pt/cim-longevit...
Excited to start as a Visiting Academic at @ucl.ac.uk ! Looking forward to collaborations and discussions with colleagues across UCL and beyond. If you're at UCL or in London, I'd love to connect and explore potential collaborations.
AI is not trained in biology, it is trained on human interpretations of biology. As such, it carries our biases, knowledge gaps, and misunderstandings. Great to discuss the impact of AI in biology and geroscience in beautiful Coimbra.
Another fantastic GRC Systems Aging conference comes to a close in Maine, USA. Thank you and congratulations to the chair and vice-chairs for organizing another incredible event, with outstanding science, networking, and discussions. My favourite conference in the field!
Today we celebrate and say farewell to outstanding postdoc, Aleksey, as he moves on to the next stage of his career. Thank you for your hard work and contributions to the lab. It has been a pleasure working with you. We wish you every success!
There is no future for anyone currently reading this if we don’t solve aging. Awesome Vision Weekend in London from the Foresight Institute discussing what the future may look like and the technologies shaping it 🚀
Great to speak at the Life Summit in Berlin. The enthusiasm around longevity is remarkable. Now we need more science and less hype. When will we have robust, data-driven interventions that truly slow human aging?
AI is transforming our lives and science, but we need to be realistic about both its promise and its limitations. It was a pleasure to speak at the Health + AI Insiders Tech Show about AI in aging science, drug repurposing, and how AI could accelerate cryobiology for regenerative medicine.
On David Attenborough’s 100th anniversary, it’s nice to remember that he once sent me a handwritten reply declining my invitation to speak at the university. His work inspired my interest in animals, evolution, and long-lived species. Happy anniversary, Sir David 🎉
Aging biology is promising, but it's still a nascent field. Great to be back at the @mpiage.bsky.social speaking with students and researchers about some uncomfortable truths: We still don't understand the drivers of aging. And caloric restriction remains the top longevity intervention.
Great to speak at Targeting Longevity 2026 in beautiful Berlin, catch up with old friends, and meet new colleagues. From genomes to systems biology and machine learning, we need robust, data-driven models to understand ageing and identify the most promising interventions.
There are definitely worse places to discuss frailty, ageing, and using AI to discover drugs that preserve health.
Had a great time visiting Coventry University! Exciting collaborations ahead 🚀
A pleasure to visit beautiful Norwich and the @uniofeastanglia.bsky.social Lovely place and wonderful colleagues. Looking forward to future collaborations!
Great discussion earlier this week at the Oxford Biohacking Society on ageing biology and where longevity science may be heading. Thank you for the thoughtful questions and lively debate 🙏
Always a pleasure to visit @imbmainz.bsky.social and learn more about the exciting research on aging, epigenetics and evolution @unimainz.bsky.social Thank you for the invitation and looking forward to fruitful collaborations 🙏
Talking genetics, aging, and the brain at beautiful Coimbra, Portugal. Neurodegenerative diseases like Alzheimer’s remain devastating and without treatment. How can we harness advances in longevity drugs and cellular rejuvenation to develop new therapies?
Had a fantastic time speaking at the NEXii Longevity Congress 2025 in my hometown of Porto! Grateful to be part of this conference exploring how longer, healthier lives will reshape our future. Big thanks to the organizers and everyone involved 🙏
Dark Prague was the perfect place to talk about longevity and fighting aging. Aging isn’t natural. It’s legacy code. A software design flaw. And we’re learning how to rewrite it.
On this Longevity Day, I questioned the field’s focus on healthspan, argued we need to be more creative and ambitious, and suggested that aging is driven not by molecular damage but by genetic programs. Had fun at TransVision 2025 in Madrid, though I may not have made many friends 😀
It was brilliant to attend the Longevity Investors conference in stunning Gstaad 🇨🇭 Everyone is aging, and age-related diseases are the major causes of mortality worldwide, yet investment in aging and longevity tech is still small. How can we increase it?
A terrific @gimmfoundation.bsky.social Festival in Lisbon. It was great to debate how to build a unifying theory of aging.
I'm very much looking forward to participating in the NEXii Longevity Congress 2025 in my hometown of Porto. NEXii 2025 will focus on the future of the longevity economy. Join me in Porto, Portugal, on 8-9 October 2025. nexiilongevity.com
Did an interview for a longevity documentary and took the opportunity to play scientist for the day 😀
I had a wonderful time in my hometown of Porto for my first conference on the history, philosophy, and social studies of biology. Grateful for the insights and conversations with biologists, philosophers, and other experts. Left with plenty to ponder about the nature and evolution of ageing.
Looking forward to the GIMM Festival on “Aging and Longevity” in Lisbon, September 4-6. Please join us in beautiful Lisbon to explore the future of aging through science. For more information and to register: gimm.pt/pt-pt/gimm-f...
Excited to be back in Oxford next week to talk about the latest discoveries and prospects in ageing research. Please join me on May 8 at 6pm at Magdalen College @ox.ac.uk To register (free): www.eventbrite.co.uk/e/the-scient...