Paul Macklin

@mathcancer

Professor of Intelligent Systems Engineering at Indiana University School of Informatics, Computing and Engineering • mathematical biologist • multicellular systems & cancer with PhysiCell • OpenSource • astrophotography Web:

1041 Siguiendo5350 Seguidores1091 Publicaciones

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Paul Macklin@mathcancer· Mar 22

This setup is designed to fit in a standard airline carry-on hard case (minus batteries and the tripod). I’m using a Nanuk 935 case with some TrekPak-style dividers.

Travel telescope in an airline carry-on case.

Paul Macklin@mathcancer· Mar 22

Now I’m testing 5 min exposures on the Monkey Head Nebula through some high altitude cloud. Using Antlia tri-band filter here.

Monkey Head Nebula (with so-so conditions including high-altitude clouds).

Paul Macklin@mathcancer· Mar 22

Testing a new Zwo AM3N mount—part of an 80mm APO travel setup. So far, guiding looks good! For reference, I have a ~2”/px imaging scale. 🔭

Paul Macklin@mathcancer· Feb 10

LOL this is how I figured the McDonald's 11 am caviar promo would turn out.

Paul Macklin@mathcancer· Feb 4

Pump finally arrived. Installed and testing. (Paper towels arw for leak testing.)

Paul Macklin@mathcancer· Jan 29

Continuing a meme: Ruin a movie by replacing one word in the title with "Sausage". Here are a few: My Sausage Lady Snow White and the Seven Sausages A Sausage Named Desire

Paul Macklin@mathcancer· Jan 26

Well, that ain't gonna' work! Now that that snow removal's done, naturally the washer failed to drain. After siphoning the water out with leftover aquarium gear and disassembling, I see the impeller completely sheared off the rusted shaft. Pump is out of production at LG, but $50 on ebay.

broken impeller on an LG washer drain pump

Paul Macklin@mathcancer· Jan 26

Just a little snow here! I measured it at about 15 inches. #snow #snowstorm

Paul Macklin@mathcancer· Jan 25

This not-spoiled, brave Corgi refused to go potty until I had dug out a path across the deck and 15 feet into the yard. #snow #snowstorm

Part of her majesty's personal snow path.

Paul Macklin@mathcancer· Jan 19

Ours says "Where's my greenie, hyoomon?"

Paul Macklin@mathcancer· Dec 27

New office decorating :-) #mathbio #mathonco 🧪 Thanks for a great 2025, @fertiglab.bsky.social @coussenslab.bsky.social @jeanettejohnson.bsky.social @heberlr.bsky.social @liz-aguilar.bsky.social @rosvall-lab.bsky.social @juncowren.bsky.social & amazing collabs! Here's to new adventures in 2026!

Office wall with 2025 Science and Cell publications, and prior astrophotography.

Science cover (2025), integrating our smart phone app for community eclipse science (over 11,000 observations across North America!) with AI analysis of audio recordings across Monroe county to detect changes in bird behavior during the eclipse.

Work led by Liz Aguilar, joint with Kim Rosvall and Dustin Reichard.

Cell article (2025) and cover submission, on our new cell behavior grammar to enable rapid, intuitive, and interpretable simulation models of complex cell systems.

Work led by Jeanette Johnson, Daniel Bergman, and Heber Rocha, jointly with Elana Fertig, Lisa Coussens, Laura Heiser, Genevieve Stein-O'Brien, and Young Hwan-Chang.

Paul Macklin@mathcancer· Nov 30

I've started some light reading of a classic. 🧪 #mathbio #mathonco I'm inspired by great collaborators with @coussenslab.bsky.social, @fertiglab.bsky.social, Laura Heiser, and others to delve deeper and improve my immunology fundamentals.

Janeway's ImmunoBiology. (Not the Federation captain who will be born in Bloomington.)

Paul Macklin@mathcancer· Nov 27

In an unusual turn of events, AI search seems to lack self confidence.

Paul Macklin@mathcancer· Nov 27

*somebody* has had a good Thanksgiving!

Paul Macklin@mathcancer· Nov 23

Just some sampling of the very fine detail.

A distant (edge-on) spiral-type galaxy, hiding in plain sight. Named PGC13696, this little guy is actually 40,000 light years in diameter and over 300 million light years away.

Paul Macklin@mathcancer· Nov 23

Pleiades (Messier 45), 2025 edition. This gorgeous reflection nebula is high This combines 36 hours of imaging on a 115mm triplet across 2024 and 2025, taken from my Indiana backyard. 🔭🧪 High-quality prints are available from mathcancer.darkroom.com/products/neb...

Pleiades (Messier 45). An incredible reflection nebula, with the blue light of hot-burning stars reflected by interstellar gas.

This image combines 36 hours of imaging taken from my Indiana backyard in Nov 2024 and Nov 2025.

Paul Macklin@mathcancer· Nov 13

It was cloudy in Bloomington last night, but we did manage to catch traces of last night's Kp7 aurora. Original photo straight off the camera (left), and minor photoshop work to bring out the pillar (right). 🔭

Kp7 aurora through clouds in Bloomington, IN on Nov 12, 2025.

Kp7 aurora through clouds in Bloomington, IN on Nov 12, 2025. Minor edits on photoshop to bring out the pillar.

Paul Macklin@mathcancer· Nov 9

Here's a faster shutter speed and increased ISO to catch the snowflakes a bit better. I definitely expect an impact on Smurf yields

Paul Macklin@mathcancer· Nov 9

It's snowing on our Smurf habitat. Smokes Smurf jerky production may be impacted.

Paul Macklin@mathcancer· Nov 4

Latte "art"

Paul Macklin@mathcancer· Oct 31

Happy Halloween! LLAP.

Paul Macklin@mathcancer· Oct 24

Honestly, speaking on a panel at the National Press Club is a bucket list item for me. What a thrill! My inner NPR nerd self is geeking out.

Paul Macklin@mathcancer· Oct 24

And now my heart friends and collaborators @fertiglab.bsky.social and Lisa Coussens are up! #NFCR 🧪

NFCR session on AI i cancer detection and prevention

Paul Macklin@mathcancer· Oct 24

Really thrilled to be at the National Press Club today for the NFCR Summit on Cancer Care. My great friend @sandyanderson.bsky.social is on the first panel on AI and cancer care. I'll be on the next panel. :-) 🧪

Panel 1 on AI and cancer care at the NFCR summit.

Paul Macklin@mathcancer· Oct 15

Always a thrill to see my dear friend @sandyanderson.bsky.social present his groundbreaking work in model-guided adaptive cancer therapy at this year's @jktgfoundation.bsky.social breast cancer symposium. 🧪

Alexander Anderson presenting model-guided adaptive therapy at JKTGF meeting

Paul Macklin@mathcancer· Oct 9

So proud of this multidisciplinary project, showing in particular the power of community science when enabled by user-friendly design, bolstering deep expertise. In the 2024 solar eclipse, 11k observations from 1700 laypeople via a jointly developed, user-friendly smartphone app.🔭🧪

Community observations of bird behaviors across the path of the 2024 total solar eclipse, via a user-friendly smartphone app.

Paul Macklin@mathcancer· Sep 27

Coffee mug Saturday! In the grand tradition of @gbosslet.bsky.social, post your Saturday mug. Thrilled this survived the flight home last week. :-)

Isaac Newton Institute for Mathematical Sciences coffee mug.

Paul Macklin@mathcancer· Sep 27

Had a nice clear moonless night in Bloomington! Getting calibration frames after a night of 180" filterless exposures on Barnard 150. 🔭

Getting 0.05" flat exposures with an LED tracing panel for astrophotography calibration.

Paul Macklin@mathcancer· Sep 26

Excited to be this week's cover for the Math Oncology Blog (# 345): a 3D @physicell.bsky.social simulation written entirely in a new model grammar without code. Jointly made with @heberlr.bsky.social, based on our recent @cp-cell.bsky.social paper. #Mathonco #mathbio 🧪 doi.org/10.1016/j.ce...

Math Onco Blog cover art 345: growing tumor attacked by tumor cells. A 3D simulation written entirely in a new model grammar without handwriting simulation code.

Paul Macklin@mathcancer· Sep 20

Feeling inspired to discover now .... (At Newton's apple tree at Cambridge, or a sapling thereof ...) 🧪