Preliminary findings using a PET tracer targeting activated astrocytes suggest a potentially revealing neuroinflammatory profile in #ME/CFS, with effects concentrated in the default mode network and possible difficulty switching out of resting networks. Watch full video here: youtu.be/BBIRZvHPc5E

For most people with ME/CFS, finding a treatment that works is trial and error. TOTEM is working to change that. Watch the full conversation between Dr. David Fineberg and Dr. Chris Armstrong here: https://youtu.be/Akp9e3smJHo?si=7x9qHZudbe0h3BcP

As May Momentum comes to a close, we want to leave you with a taste of why our researchers do what they do. Watch the full conversation here: https://youtu.be/FPhECAf7gz0

Today at the Invest in ME Conference, Dr. Maureen Hanson — member of OMF's Scientific Advisory Board — presented "Searching for Chronic Infection in ME." Thank you, Dr. Hanson, for the research that moves us closer to answers for the millions living with ME/CFS.

Linda Tannenbaum, Founder and CEO of OMF, will deliver the inaugural lecture of Faculty of Medicine of the University of Lisbon’s new Open Lectures series on May 25.

May 12 marks International ME/CFS Awareness Day. This year we asked our community to share the questions they live with because of #MECFS. Here are some of their responses. Visit https://www.omf.ngo/maymomentum/ to join us in raising awareness. #MECFSis #MECFSAwareness

Imagine the worst flu you've ever had and it never goes away." That's how Linda Tannenbaum of Open Medicine Foundation describes ME/CFS — a chronic illness with no blood test, few treatments, and a shortage of trained doctors. Read the full story: https://ow.ly/WSWs50YQR9f

Digital health in clinical research means using tools like smartphone apps and wearable devices to help people take part in studies. OMF’s Melbourne ME/CFS Collaboration has developed a novel digital health tool as part of their Personalized Treatment Trials project. 👉 https://ow.ly/30x750YCVFp

🔬Help advance #MECFS and #LongCOVID research by joining OMF’s StudyME, a free global participant registry that connects you with researchers conducting studies in these areas. 👉 Sign up today: https://www.omf.ngo/studyme/ #UnitedForME #MECFSresearch #POTS #pwME #pwLC

A heartfelt thank you to our OMF community💙 In March, we welcomed 37 new Hope Builders, surpassing our goal of 30! Your support—whether through monthly donations or engaging in other ways—is helping us make progress in #MECFS and #LongCOVID research and medical education. 🌟

🧬Science Wednesdays: Repeatable vs reliable At OMF’s Melbourne ME/CFS Collaboration, the team is assessing the repeatability and reliability of the FUNCAP questionnaire as a measure of in-the-moment functional capacity. 🔗 https://www.omf.ngo/repeatable-vs-reliable/

⏰ Last Chance to Join Our March Hope Builders Challenge There are just 24 hours left to join the Hope Builders and make a lasting impact. We’re just three supporters away—will you be the one to help us cross the finish line? 💙 Become a Hope Builder today: https://ow.ly/JEIp50YAJut

Nearly 20 years ago, Donni opened her own kindergarten. Four years in, everything changed. 🤝 She now supports OMF to find real answers for #MECFS & #LongCOVID. 🔗 Read Donni's story and join Hope Builders: https://www.omf.ngo/donni-beyond-the-glass/ ART: “BEYOND THE GLASS” by Donni

Data artifacts are flaws or distortions in data, resulting from things like how the data were collected or processed. 👉 Read more about data artifacts in #MECFS research and OMF’s Computational Research Center: https://www.omf.ngo/data-artifacts/.

🌸 Spring into giving and make a lasting impact by donating your vehicle to OMF. It's easy, free, and tax-deductible. Learn more: https://ow.ly/gKnA50YybGP

OMF invites you to join our community of Hope Builders — compassionate individuals who support OMF's research with a monthly gift of just $5 or more. Become a Hope Builder today 👉 https://ow.ly/q4G450YxGse. Thank you for your support!

Tina is one of the Hope Builders — monthly donors whose collective support helps keep OMF's research moving forward. This March, we're welcoming 30 new Hope Builders. Will you join us? 👉 Read Tina's story and become a Hope Builder: https://www.omf.ngo/tina-mecfs-story/

🗣️ Your voice matters! By sharing your story, you help raise awareness and deepen understanding of #MECFS, #LongCOVID, and related diseases. Whether you're a patient, caregiver, family member, or friend, your experience is important. Submit your story today 👉 https://www.omf.ngo/voices-of-m-e/

Today is #LongCOVIDAwarenessDay — a moment to recognize the reality facing hundreds of millions worldwide. 🌎 #LongCOVID is not a disease fading into the past. For many, it is a daily struggle with no clear end and no approved treatment in sight. 🔗 https://www.omf.ngo/2026-long-covid-awareness-day

From the OMF-supported MERC with @BatemanHorne: During a crash, #pwME may struggle to think or communicate clearly. Communication cards help patients point to needs like water, pain, light sensitivity, or emergencies. Find these cards in our Crash Survival Guide: https://bit.ly/44MgSS9

💙 Will you take the next step with us? Join our community of Hope Builders by becoming a monthly donor to #OMF!! 👉 https://ow.ly/aJCP50VjlWq Your support fuels #MECFS and #LongCOVID research, bringing us closer to solutions.

🧬Science Wednesdays: Estimating Lifetime Prevalence of #MECFS Based on published research, the lifetime prevalence of ME/CFS is over 279 million people, which is around 1 in 29. 🔗 Read more about lifetime prevalence of ME/CFS: https://ow.ly/iR4q50Ysroa

📚OMF Journal Club: March 11 at 11 am ET Dr. Meadows will discuss the latest paper from Dr. Jonas Bergquist and collaborators: "Plasma proteomic profile reveals persistent immune activation in post-acute sequelae of SARS-CoV-2 infection (PASC)." 👉 Sign up: https://ow.ly/qyW950YrjKe

From his bed, Sebastian creates Drum & Bass 🎶 Two years ago, he was active, sporty, and highly driven. Today, he is around 90% bedbound. He works on music when he can & his work has reached over 1.5 million streams on Spotify. Read Sebastian's story👉 https://ow.ly/n2KZ50YpIqX.

Hope for people with #MECFS and #LongCOVID starts with research. When you become a monthly donor — a Hope Builder — you provide steady support that helps sustain critical research programs and move discoveries forward. 👉 Become a Hope Builder today: https://ow.ly/V98M50YpHsm

In the context of research, calling something “significant” is a statistical description. It’s a term that indicates it’s unlikely that random chance could explain a result. 🔗Learn more about calculating significance in #MECFS research: https://www.omf.ngo/significant/

Dr. Bergquist & his collaborators published a paper looking at protein levels in people with post-acute sequelae of SARS-CoV-2 infection and controls who recovered from a SARS-CoV-2 infection. 🔗 Learn more about this publication and the next Journal Club: https://ow.ly/mwbX50YoHEn

In 2025, OMF launched a large-scale #MECFS biomarker project called BioQuest. Cort Johnson’s article explores the study and includes insights from Dr. Danielle Meadows, OMF’s Vice President of Research Programs & Operations. 🔗 Read the article here: https://ow.ly/zgGn50YocTW

🤝 Be a Catalyst for Change: Join Hope Builders Hope Builders are our cherished monthly donors. This March, we’ve embarked on a mission to welcome 30 new Hope Builders by the month’s end. Will you be one of them? 💙Join us and fuel progress: https://ow.ly/Ep7m50YnEOO

Encephalopathy generally describes a condition that affects brain function. There are different causes of it, including infection, exposure to toxins & more. Learn more about encephalopathy and the Uppsala CRC investigation into post-viral encephalopathy: https://www.omf.ngo/encephalopathy/