New podcast episode just dropped 💥: Learn how AI and machine learning are transforming cancer research and care. https://ow.ly/Ee6i50Zuqs9

How Do I Know if a Clinical Trial Is Right for Me? A comic explaining the risks and benefits of participating in a cancer clinical trial, translated for a Polish-speaking audience.

Zhang et al., published a new article in #JCOPrecisionOncology highlighting the potential of cfDNA-derived 5-hydroxymethycytosine signatures as a noninvasive prognostic biomarker in newly diagnosed multiple myeloma. @uchicagomedicine.bsky.social https://ow.ly/4ekN50ZtAg9

🔥Hot off the press: The University of Chicago researchers show reduced pancreatic tumor growth using engineered Bifidobacterium to produce super mutant IL-2 that activates tumor-fighting T cells. UChicago Pritzker Molecular Engineering https://ow.ly/9cvS50Zs61j

Dr. Mark Ratain offers perspective on the recent retraction of a @NatureMedicine paper, underscoring the importance of data integrity, rigorous clinical trial design, and transparency in advancing cancer research and patient care. @uchicagomedicine.bsky.social https://ow.ly/EIjj50ZnVLZ

In the latest episode of BackTable Tumor Board, Drs. Chih-Yi Liao and Xavier Keutgen discuss the key steps involved in the diagnosis and management of neuroendocrine tumors, from staging and imaging to treatment decisions. @uchicagomedicine.bsky.social https://ow.ly/6O3e50Zntax

Singh et al. published a new study in NPJ Precision Oncology identifying progressive transcriptional reprogramming as a driver of the malignant transformation of IP-SNSCC. @uchicagomedicine.bsky.social Nature Portfolio https://www.nature.com/articles/s41698-026-01599-4

Helping cancer patients quit smoking has been sidelined for too long. No Smoker Left Behind Initiative led by Dr. Andrea King shows proactive, evidence-based cessation care can reach diverse cancer populations and work in real-world settings. Healio https://ow.ly/JSrn50Zm3L7

Recently the FDA approved the combination of belzutifan and pembrolizumab as an adjuvant treatment for adults with clear cell renal cell carcinoma who are at an intermediate-high or high risk of recurrence after surgery. https://www.survivornet.com/articles/v/

Rita Nanda, MD, said the FDA approval of sacituzumab-based therapy for the first-line treatment of metastatic TNBC gives patients and their care teams an important new option at the very beginning of their treatment journey. https://ow.ly/Z4UQ50ZlKQv

Bone and soft tissue cancer can be frightening for children and adults. However, the latest treatments available at UChicago Medicine — from innovative chemotherapy to limb-sparing surgery — can reduce pain, fight the disease and preserve the ability to walk, work or play. https://ow.ly/Rc6A50Zlf3k

Kudos to Benjamin Shogan, MD, and colleagues on publishing a new study in Nature Communications, demonstrating antimicrobial resistance and collagen producing bacteria as a prognostic biomarker for postoperative oncologic outcomes in colorectal cancer recurrence. https://ow.ly/mlAQ50ZlcGU

Happy Fourth of July from the UChicago Medicine Comprehensive Cancer Center! Today, we celebrate independence, resilience and community while honoring the patients, families, caregivers, researchers and care teams who inspire us every day. Wishing everyone a safe holiday!

Join us in congratulating Scott Oakes, MD, who has been named the first Frank W. Fitch Professor in the Department of Pathology. Dr. Scott's work has advanced understanding of stress-signaling pathways in cancer, diabetes and other diseases. University of Chicago Pathology https://ow.ly/JFak50ZjG37

In a new study, Jeff Rathmell, PhD, and colleagues demonstrate that MMP is increased in exhausted T cells, suggesting MMP may serve as a biomarker for monitoring responses to immunotherapy treatment. The Journal of Immunology https://ow.ly/yUbl50ZigXB

Jung Woo Kwon, MD, and colleagues published a new study showing that a subset of usual-type penile squamous cell carcinoma (pSCC) are positive for HPV, suggesting routine HPV testing in all pSCCs with the usual-type morphology. https://ow.ly/M08a50ZhfwH

Today, the AACR released its Cancer Disparities Progress Report, a comprehensive analysis of the unequal burden of cancer in the US. The report highlights both the progress made and the persistent disparities affecting medically underserved populations. www.CancerDisparitiesProgressReport.org

In our latest podcast episode, two prominent cancer leaders, Dr. Soni Smith and Dr. Kay Macleod discuss how strong, collaborative leadership at UChicago is driving innovation and shaping the future of cancer research and patient care. https://ow.ly/ML0B50Zg0wQ

New research in JAMA Oncology from the WISDOM Study highlights the importance of population-based pathogenic variant testing in risk-based breast cancer screening. #PolygenicRiskScores #BreastCancerRisk @uchicagoobgyn.bsky.social @uchicagomedicine.bsky.social https://ow.ly/aRAO50Zfpmk

The new AbbVie Foundation Cancer Pavilion, Illinois’ first freestanding cancer care facility, is set to open in April 2027. Construction crew members reflect on the meaningful connection they’ve built while bringing this purpose-driven facility to life. https://ow.ly/c4It50ZecKt

🔥Hot off the press: Sun et al. published a new study in JAMA Network Open reporting a 162-variant TNBC PRS that showed the best discrimination and offers a promising, more equitable approach to genetic testing for women of African ancestry. @uchicagomedicine.bsky.social https://ow.ly/lKA950ZcQcJ

June is #NationalCancerSurvivorMonth! At UChicago Cancer, survivorship care continues beyond treatment. To every cancer survivor, caregiver, loved one and care team member, we honor your journey and stand with you every step of the way. #LifeAfterCancer https://ow.ly/8wQe50ZbRS0

Alex Pearson, MD, PhD, and colleagues reports that prompt direct ambient AI improves quality of summaries as compared to manual or ambient AI generated documents during head and neck tumor board discussions. @uchicagomedicine.bsky.social https://ow.ly/fvBc50Zb8sw

UChicago Cancer faculty and trainees showcased at #ASCO2026, the world's largest oncology conference, with presentations spanning from practice-changing clinical trials, genetic testing, palliative care, AI-driven drug discovery, and cancer prevention. https://ow.ly/srga50ZaAhY

Ardaman Shergill, MD, and colleagues report that early-onset appendiceal adenocarcinoma may be a distinct subtype, highlighting the need for larger prospective studies to guide clinical management. Annals of Surgical Oncology https://ow.ly/1Zt650Zayvv

Slideflow Labs, an AI pathology company spun out of a research lab at UChicago, is revolutionizing cancer care through its advanced biomarker development and deployment directly into hospital settings. University of Chicago Pathology @uchicagomedicine.bsky.social https://ow.ly/SN3a50Za57e

The recent issue of NCCN guidelines for #BladderCancer specially covers the clinical presentation and subsequent management recommendations for non-muscle-invasive bladder cancer. @uchicagomedicine.bsky.social Check out the full version here: https://ow.ly/OxOY50Z9oEG

Congratulations to #SlideflowLabs, a UChicago spun out cancer pathology AI company on winning Rattan L. Khosa First Place Prize. #SlideflowLabs enables hospitals to run cancer biomarkers in-house with faster turnaround times. University of Chicago Pathology https://ow.ly/eTYS50Z8NRA

National Cancer Survivors Day is a day to recognize cancer survivors, to raise awareness of the ongoing challenges cancer survivors face because of their disease, and – most importantly – to celebrate life. #NCSD2026 ncsd.org

Join us in congratulating our faculty members recognized with 2026 UChicagoBSD Faculty Awards for their outstanding contributions to education, research, program innovation, community service, and patient care. @uchicagomedicine.bsky.social