Brian H Mathison
@allthingstox
Father, husband, scientist, & toxicologist; BA Biochem & Molecular Biology (UCSB); PhD Environmental Toxicology (UCI) 🧬Composite Transcription Factor Decoys. Chemical Carcinogenesis, Genetic Toxicology, & Predictive Technologies brianhmathison.substack.com
Looks like 16+ briefs filed today in Monsanto v Durnell. Few actually addressing the question before the court. Glyphosate toxicology is not being adjudicated. Pretty crazy. www.supremecourt.gov/docket/docke...
Maybe journalists could do better as when 4 Johns Hopkins Livable Future authors cite Zhang’s meta‑analysis, note that EPA HED and Judge Chhabria found serious methodological flaws, calling it effectively 'junk science.' Yet outlets like SciAm, CNN, and The Guardian still report it & omit ECHA/EFSA.
I’d disagree. Classic lies of omission shouldn’t be the bar by which professional journalism is judged adequate, when truth, fairness, independence, & accountability are routinely missing in glyphosate coverage. The IARC Monograph program cannot be compared to world regulatory authorities.
NotebookLM graphics can take pages of text and references and turn them into a surprisingly good visual that captures the main points I’d try to make. A picture really can be worth a 1000 words & sometimes it makes clear that the confident takes on social media missed the point.
Durnell v Monsanto, Glyphosate I've uploaded several rulings, briefs, and some of my additional writings, then asked for a “graphic summary,” and it wasn’t awful. I’ll expand on Substack in time, especially regarding monograph program limitations compared to regulatory consensus.
Lot’s on my mind, but like seeing Shadow, Jackie, and Punch coverage.
Glyphosate: Hitting New Lows in Journalism It is hard to know what is deteriorating faster, journalistic rigor or public understanding of science.
Not surprised glyphosate came up in this morning’s confirmation hearing for Casey Means. The real question: will the coverage dig into the actual science and regulatory record or just recycle the usual talking points? substack.com/@allthingsto...
Nope, "Reminder: Glyphosate is not carcinogenic, mutagenic, or reprotoxic, as concluded by the most recent scientific assessments by EFSA/ECHA. While acknowledging knowledge gaps, these assessments represent the most comprehensive evaluation of a pesticide ever conducted."
Reminder: Glyphosate is not carcinogenic, mutagenic, or reprotoxic, as concluded by the most recent scientific assessments by EFSA/ECHA. While acknowledging knowledge gaps, these assessments represent the most comprehensive evaluation of a pesticide ever conducted. www.efsa.europa.eu/sites/defaul...
The glyphosate saga is remarkable on many levels. Expert testimony proved essential, including that of toxicologist William Sawyer in Pilliod v. Monsanto Co., a case that produced a verdict exceeding $2 billion and ultimately contributed to more than $10 billion in settlements.
Yes, there’s a strange disconnect with some computational tools. Writing Python, using RDKit, or fetching a PubChem CID is easy, yet several publications (and posts) still miss basic biology & chemistry (e.g., like zwitterionic forms in the human body). pubchem.ncbi.nlm.nih.gov/compound/248...
Best to cite EFSA and ECHA, which conducted the most comprehensive glyphosate assessments and found no critical health concerns for carcinogenicity, mutagenicity, or reproductive toxicity (while acknowledging data gaps), then ask why the NYT article omits this. www.efsa.europa.eu/sites/defaul...
EFSA and ECHA conducted the most exhaustive glyphosate evaluation to date, reviewing vast evidence and finding no critical health concerns like carcinogenicity, mutagenicity, or reprotoxicity, even while noting data gaps. Why does the NYT article omit this? www.efsa.europa.eu/sites/defaul...
Glyphosate / Roundup Litigation Update Monsanto v. Durnell (No. 24-1068) was distributed for conference today (Dec. 16, 2025). Respondent also filed a 13-page supplemental brief today. A decision on certiorari pending w/ conference date of Jan. 9, 2026. substack.com/@allthingsto...
About 1 in 5 adults globally still use tobacco products (as of the 2024 data from WHO) - many remain at risk of the many harms associated with tobacco use. www.who.int/publications...
Nope, 1802 – Hôpital des Enfants Malades (Paris, France) 1852 – Great Ormond Street Hospital (London, England) 1855 – Children’s Hospital of Philadelphia (CHOP, USA) ourworldindata.org/child-mortal...
Perplexity AI, Synthetic Certainty, & Glyphosate substack.com/@allthingsto...
Casey Means hearing next week - some thoughts substack.com/@allthingsto...
Glyphosate update: [~1,188 words, or ~27 tweet equivalents, posts always fleeting here] substack.com/@allthingsto...
Lead and Protein Powder - IRONY AHEAD substack.com/profile/1098...
Generative Artificial Intelligence (GAI) - Yikes Note: substack.com/profile/1098...
Was hoping to hear more about possible solutions & didn’t catch any thoughts on the Surgeon General nominee? Cabinet secretaries serve at the pleasure of the president, and even with the current polling, we may be in for a few more years. Each day a new adventure. www.pewresearch.org/short-reads/...
Fleeting thoughts on toxicology open.substack.com/pub/brianhma...