Deupirfenidone compared with pirfenidone and placebo in idiopathic pulmonary fibrosis (ELEVATE-IPF): a phase 2b randomized placebo-controlled trial Deupirfenidone slowed the rate of FVC decline compared with placebo in IPF doi.org/10.1093/ajrc... @atscommunity.bsky.social

Rocuronium dose and first-attempt intubation success in the critically ill: secondary analysis of two multicenter trials Among adults undergoing intubation with rocuronium, those receiving doses >1.2 mg/kg had higher first-pass success doi.org/10.1093/ajrc... @atscommunity.bsky.social

Optimizing endpoints in early phase clinical trials of acute respiratory distress syndrome doi.org/10.1093/ajrc... @atscommunity.bsky.social

Discriminative performance and clinical utility of chronic obstructive pulmonary disease exacerbation categories for predicting future exacerbations doi.org/10.1093/ajrc... @suryapbhatt.bsky.social @atscommunity.bsky.social

The August issue of #AJRCCM is now live! Take a look: academic.oup.com/ajrccm/issue... @atscommunity.bsky.social

📢 One Month Left! Apply to become the next Editor-in-Chief of AJRCCM Learn more here: tinyurl.com/42mmsmah @atscommunity.bsky.social

BAL-derived extracellular vesicles to test ex vivo for endothelial injury in HIV patients on antiretroviral therapy doi.org/10.1093/ajrc... @atscommunity.bsky.social

10 mL/kg vs 20 mL/kg fluid bolus in pediatric septic shock: a randomized clinical trial In pediatric septic shock, 10 mL/kg vs 20 mL/kg fluid boluses showed similar early outcomes, with less fluid overload at 24 hours doi.org/10.1093/ajrc... @atscommunity.bsky.social

Relative contribution of driving pressure and respiratory rate to mortality in ARDS depends on age As age advances, driving pressure becomes relatively more important than respiratory rate to mortality in ARDS doi.org/10.1093/ajrc... @atscommunity.bsky.social

Safety and antimicrobial efficacy of CSL787, a novel nebulized IgG therapy, in patients with bronchiectasis: results from a randomized phase 1 trial Inhaled immunoglobulin is safe in bronchiectasis and may reduce bacterial load and symptoms doi.org/10.1093/ajrc... @atscommunity.bsky.social

Understanding firefighter qualification under race-neutral spirometry and evolving National Fire Protection Association guidelines doi.org/10.1093/ajrc... @atscommunity.bsky.social

Impact of adopting race-neutral lung function reference equations on firefighter hiring doi.org/10.1093/ajrc... @atscommunity.bluesky

A large-scale single-cell atlas reveals the pulmonary immune panorama in adult patients with influenza doi.org/10.1093/ajrc... @atscommunity.bsky.social

A statistical model for lung function trajectory and mortality in patients with fibrotic interstitial lung disease doi.org/10.1093/ajrc... @atscommunity.bsky.social

Idiopathic pulmonary fibrosis risk loci in East Asian populations mirror those of European populations doi.org/10.1093/ajrc... @atscommunity.bsky.social

Effects of an early restrictive versus liberal fluid strategy on long-term patient-centered outcomes in sepsis-induced hypotension: an open-label, randomized controlled trial doi.org/10.1093/ajrc... @atscommunity.bsky.social

Mosaic loss of Y chromosome associates with lung function, emphysema, and epigenetic aging doi.org/10.1093/ajrc... @atscommunity.bsky.social

A precision approach to translational research in acute lung injury doi.org/10.1093/ajrc... @atscommunity.bsky.social

Disseminating Research Success Via ATS Journals Stephanie D. Davis, MD, Chair of the ATS Publications Policy Committee, speaks about the work of the ATS Journals 📺Watch the interview here: tinyurl.com/2u73jncu @atscommunity.bsky.social

Mast cells and endothelial cells mediate interleukin-33 and ST2 responses in distal COPD lungs This study reveals important new insights into the spatial and cellular dynamics of IL-33 and ST2 splice variants in distal COPD lungs doi.org/10.1093/ajrc... @atscommunity.bsky.social

Delirium in the context of the other brain reaction types The authors reframe delirium as an arousal disorder within a spectrum of brain reactions, clarifying phenotypes and reducing imprecision doi.org/10.1093/ajrc... @atscommunity.bsky.social

Aroxybutynin and atomoxetine (AD109) for obstructive sleep apnea: a randomized phase 3 trial (SynAIRgy) Positive phase 3 results showed that the oral pill AD109 improved airway obstruction and oxygenation across OSA disease severity doi.org/10.1093/ajrc... @atscommunity.bsky.social

A statistical model for lung function trajectory and mortality in patients with fibrotic interstitial lung disease A new model for evaluating treatments in ILD holds promise for improving the accuracy and efficiency of clinical trials doi.org/10.1093/ajrc... @rogerjlewis.bsky.social

Role of casual contact in drug-resistant tuberculosis transmission: a molecular epidemiology study doi.org/10.1093/ajrc... @emoryrollins.bsky.social @atscommunity.bsky.social

Mesotype–the missing link between phenotype and endotype in asthma doi.org/10.1093/ajrc... @atscommunity.bsky.social

US Air Quality Index and respiratory health outcomes: background, knowledge gaps, and research prioritization: an Official American Thoracic Society Research Statement doi.org/10.1093/ajrc... @ats-eoph.bsky.social @atscommunity.bsky.social

The July issue of #AJRCCM is now live! Take a look: academic.oup.com/ajrccm/issue... @atscommunity.bsky.social

📢AJRCCM Call for Papers on Critical Care The March 2027 issue of AJRCCM will feature a special section devoted to critical care. Submit your manuscript by October 31, 2026. @atscritcare.bsky.social @atscommunity.bsky.social

Extracellular vesicle cargo from lipofibroblasts mitigates COPD by alveolar type 2 cell restoration Lipofibroblast EVs restore alveolar type II cells and mitigate COPD, pointing to a new regenerative therapy doi.org/10.1093/ajrc... @atscommunity.bsky.social

Standalone prognostication of idiopathic pulmonary fibrosis using attention-based deep learning From a single baseline CT scan, ORACLE-IPF can predict five-year mortality risk in patients with IPF, advancing established prognostic markers doi.org/10.1093/ajrc... @atscommunity.bsky.social