Department of Biomedicine🔬🧪

@biomedizin

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance our understanding of health and disease.

72 Folgt240 Follower79 Posts

Bluesky

Ist das dein Profil?Übernimm es — dann gehört dir biomedizin.dirty.social.Profil übernehmen

Department of Biomedicine🔬🧪@biomedizin· 14d

New in @jamaneurology.com: Jens Kuhle from @biomedizin.unibas.ch, @unibas.ch and @dkf.unibas.ch together with other colleagues shows that the blood biomarker GFAP is associated with progression independent of relapses in multiple sclerosis and may complement NfL. Congratulations to the team! 👏👇

Data from thousands of blood samples allowed the researchers to compare different biological processes involved in multiple sclerosis. (Photo: Kathleen Herrgott, RC2NB)

Department of Biomedicine🔬🧪@biomedizin· 21d

Dr. @mariuslange.bsky.social has been appointed Tenure-Track Assistant Professor of Systems Developmental Medicine. He combines computational biology & single-cell genomics to study how human tissues & organs develop, thereby advancing our understanding of early childhood development. 👇

Department of Biomedicine🔬🧪@biomedizin· Jul 14

🧠 Great news from the Molecular Neuroscience Lab! Professor Andreas Papassotiropoulos has been elected to the German National Academy of Sciences Leopoldina — one of the most prestigious scientific honors in the German-speaking world. Congratulations, Andreas! 🎉 biomedizin.unibas.ch/en/newsdetai...

Department of Biomedicine🔬🧪@biomedizin· Jun 30

Another ERC success for @biomedizin.unibas.ch: Judith Zaugg has been awarded an #ERCPoC Grant for HemaTrax, a project improving the prediction of blood toxicity in cancer therapy and drug development. It could support safer treatments and speed up the development of new therapies. 👍 @erc.europa.eu

Department of Biomedicine🔬🧪@biomedizin· May 29

🔬 Two new studies from the Pinschewer Lab at the DBM shed new light on antiviral immunity — from Lassa fever vaccination to B cell “attrition” in chronic infection. Congratulations to the team! 👏 Nature Communications: www.nature.com/articles/s41... PNAS: www.pnas.org/doi/10.1073/...

Fluorescence microscopy of mouse spleen tissue comparing chronic infection with a virus to which adoptively transferred B cells bind with high affinity (top) versus infection with a virus bound at low affinity (bottom). Green marks the transferred B cells, red the germinal centers where B cells mature, white the surrounding B cell zone. (Dimitrova et al., PNAS 2026, Fig. 2H–I. Reproduced under CC BY licence.)

Department of Biomedicine🔬🧪@biomedizin· Apr 17

MISEV2023 sets key guidelines for EV research. With contributions from Edveena Hanser, Diego Kyburz, & an international consortium, the paper is now one of the top ten most-cited papers in JEV (Wiley, 2024). Congratulations to everyone involved. isevjournals.onlinelibrary.wiley.com/doi/10.1002/...

Department of Biomedicine🔬🧪@biomedizin· Apr 10

📺 TV tip The ZDF documentary “plan b: A fresh start for the knee” features research from the @biomedizin.unibas.ch , @unibas.ch, on cartilage regeneration using patients’ own cells. 📅 10 April, 19:40 (ARTE) and 12 April, 15:30 (ZDF) Also available online. Link in comments. @dkf.unibas.ch

Department of Biomedicine🔬🧪@biomedizin· Apr 1

Welcome on board @Frauke von Versen. We are happy to have you with us, and we wish you a great start! #Welcome2026 #welcometotheteam #welcomeonboard #TeamDBM @biomedizin.unibas.ch n.unibas.ch DBM News: 👉 biomedizin.unibas.ch/en/newsdetai...

Department of Biomedicine🔬🧪@biomedizin· Mar 31

Aβ and tau disrupt memory circuits in Alzheimer’s disease. New work from the @marcaurelbusche.bsky.social Lab at @biomedizin.unibas.ch .ch and @uclhresearch.bsky.social bsky.social links this to synaptic NMDA receptor hypofunction and shows recovery when both pathologies are reduced. 🔗See comments.

Department of Biomedicine🔬🧪@biomedizin· Mar 10

🔬 Science moves forward through collaboration! Researchers from @biomedizin.unibas.ch and the Department of Pharmaceutical Sciences (DPhW) came together for the DBM–DPhW Joint Meeting 2026 — a day of inspiring talks, exchange, and new connections across disciplines. 👏 #DBM #DPhW #LifeSciences

Department of Biomedicine🔬🧪@biomedizin· Mar 3

Today, we’ve officially launched the Xenium platform at @biomedizin.unibas.ch in collaboration with @bsse.ethz.ch. 🚀 A major step forward for spatial transcriptomics in Basel! 👉 biomedizin.unibas.ch/en/communica...

Department of Biomedicine🔬🧪@biomedizin· Feb 13

On Wednesday, we hosted the symposium, “Sex & Gender Differences in Medicine & Research,” with Athena’s Journey. Sex & gender influence disease risk, symptoms & outcomes - yet they are underrepresented in research. Integrating them isn’t optional. It’s essential. #SexandGender #ClosingTheGap #IDWGS

Department of Biomedicine🔬🧪@biomedizin· Jan 23

DBM Research Day 2026 has wrapped up! 🎉 There were great talks and lively discussions, as well as an excellent poster session showcasing emerging research across DBM. Thanks to everyone involved! See you in 2027! #DBMResearchDay #Science #TeamDBM @biomedizin.unibas.ch

Department of Biomedicine🔬🧪@biomedizin· Jan 20

How does aggressive AML originate? A new study shows that thrombopoietin can prime EVI1+ stem cells, making them more vulnerable to KMT2A fusion–driven leukemia, published in @natcomms.nature.com from the Schwaller lab @biomedizin.unibas.ch. 👉 www.nature.com/articles/s41... #AML @unibas.ch

Wright-Giemsa stained cytospin preparations of murine long-term hematopoietic stem cells. (Image: Hugues-Étienne Châtel-Soulet, University of Basel).

Department of Biomedicine🔬🧪@biomedizin· Jan 14

How can a common virus contribute to a rare disease? A new @cp-immunity.bsky.social study from @biomedizin.unibas.ch links EBV to early MS-like lesion formation by showing how B cells can act at the very start of the disease process. 🔗 doi.org/10.1016/j.ce... @unibas.ch #EBV #MultipleSclerosis

Confocal micrograph of the mouse brain. The myelin sheaths that wrap the the axons of neurons are shown in red. The blue cells are infected with a virus. Such infections cause immune cells to enter the brain. If these immune cells attack the myelin, autoimmune disease can result. Image by Hyein Kim (University of Basel).

Department of Biomedicine🔬🧪@biomedizin· Jan 12

Two back-to-back BJH papers from the XPAG-ITP trial! 🎉 ETB+dexamethasone showed longer response & less rescue therapy vs dex alone in ITP. Immune profiling reveals baseline TCR clonality predicts durable remission. 🔗 onlinelibrary.wiley.com/doi/10.1111/... #ITP #Hematology #TranslationalResearch

Artistic rendering of platelets and immune cells highlighting immune dynamics in immune thrombocytopenia. Generated with AI.

Department of Biomedicine🔬🧪@biomedizin· Jan 9

How can we tell whether an antibiotic eradicates an infection? Researchers from the @biomedizin.unibas.ch, at the @unibas.ch, present an antimicrobial single-cell microscopy-based method that measures antibiotic lethality in individual bacteria. 🔗 doi.org/10.1038/s415... @natmicrobiol.nature.com

Some bacterial pathogens play dead to dodge antibiotics. A new test watches them closely—and helps choose drugs that finish the job. (Symbolic image: Adobe Stock)

Department of Biomedicine🔬🧪@biomedizin· Dec 23

As we wrap up 2025, we’re wishing you peaceful days filled with rest, joy, and good company. 🌟 Thank you for being part of our community this year. Happy Holidays and all the very best for 2026 — from all of us at the @ biomedizin.unibas.ch ! #HappyHolidays #NewYear2026 #Biomedicine #UniBasel

Department of Biomedicine🔬🧪@biomedizin· Nov 18

Our Tissue Engineering Lab has built the most advanced human bone marrow model! It supports blood cell formation, reduces the need for animal testing, and could one day aid drug testing and personalized cancer treatments. 👉 www.cell.com/cell-stem-ce... #TissueEngeneering #HumanBoneMarrowModel

Scanning electron microscopy image of the engineered 3D bone marrow tissue colonized with human blood cells (red). (Image: Andrés García García, University of Basel, Department of Biomedicine).

Department of Biomedicine🔬🧪@biomedizin· Oct 24

New multicenter study from the RC2NB including members of the DBM shows granulocyte & astrocyte markers in CSF can clearly distinguish MOGAD and NMOSD from MS. 👉🏻 doi.org/10.1093/brai... #Neuroimmunology #MOGAD #NMOSD #MS #Biomarkers

Dynamic neural pathway simulation with flashing white patches highlighting demyelination (Image Adobe Stock).

Department of Biomedicine🔬🧪@biomedizin· Oct 22

New findings in Science Translational Medicine reveal distinct immune signatures in MOGAD, distinguishing it from MS and pointing toward disease-specific therapies. Kudos to all involved. 👉🏻 www.science.org/doi/10.1126/... #MOGAD #Neuroinflammation #MSResearch

Visual representation of neuroinflammation: red, reactive immune activity disrupting the normal blue neural network. The image symbolizes the immune dysregulation underlying MOG antibody–associated disease (MOGAD). Image Adobe Stock.

Department of Biomedicine🔬🧪@biomedizin· Oct 21

Immune clues in tumors and blood predict who benefits from neoadjuvant chemoimmunotherapy in lung cancer. Congrats to the Zippelius Lab! www.nature.com/articles/s41... @nature.com #LungCancer #Immunotherapy #CancerResearch #Oncology #PrecisionMedicine

Microscopy images showing three separate areas of a lung tumor, representing different immune environments: desert, excluded, and inflamed. These are general examples used to illustrate how immune cells interact with tumors. The top row displays a CD8 immunohistochemistry image, while the bottom row shows a marked version where CD8+ T cells are highlighted in red and tumor cells in blue. Adopted from Schmid, D., et al. (2025), Nature Communications.

Department of Biomedicine🔬🧪@biomedizin· Oct 1

🚀 Breakthrough in #ProstateCancer research from @biomedizin.unibas.ch published in @cp-cellreports.bsky.social! Matrigel-free PDOs preserve patient-specific cell populations. New single-cell atlas (PPScA) maps heterogeneity + reveals pathways altered in vitro.

Fluorescent microscopy image of antibody-labeled patient-derived organoids (PDOs), captured at Le Magnen Lab.

Department of Biomedicine🔬🧪@biomedizin· Sep 18

Researchers @biomedizin.unibas.ch developed cartilage implants from nasal septum cells, and showed that allowing them to mature for two weeks improved outcomes. 🔬Congratulations to all contributors. doi.org/10.1126/scit... #Immunotherapy #CancerImmunology #FusionProtein #PD1IL2v #TCellTherapy

© Martin Oeggerli (www.Micronaut.ch) 2019-2025, with Marcel Philipp Trefny, and Prof. Alfred Zippelius, Cancer Immunology, University Hospital Basel, Pathology University Hospital Basel, and C-CINA, Biozentrum, University Basel

Department of Biomedicine🔬🧪@biomedizin· Sep 12

New in Haematologica: Researchers at binderlab.bsky.social report a mutation-specific immunotherapy for high-risk CLL. A bispecific antibody (BiTE) redirects T cells to target IGLV3-21^R110+ leukemia cells—killing malignant cells while sparing healthy B cells. Link: doi.org/10.3324/haem...

Bispecific antibodies as a potential off-the-shelf immunotherapy for high-risk CLL patients (Image Adobe Stock)

Department of Biomedicine🔬🧪@biomedizin· Sep 4

Four DBM researchers at the University of Basel just secured ERC Starting Grants!🎉 A huge congratulations to Jean-Christophe Beltra, Mariana Borsa @nanaborsa.bsky.social , Magdalena Sznurkowska & Tobias Weiss. 🔗 Full news: biomedizin.unibas.ch/en/communica... @erc.europa.eu #ERCStG

Department of Biomedicine🔬🧪@biomedizin· Sep 2

🚀 Welcome Prof. Dr. Marc Aurel Busche @marcaurelbusche.bsky.social to the DBM, University of Basel! He’ll head the Brain Ageing & Neurodegeneration Lab, focusing on Alzheimer’s and brain circuit dysfunction. Read more: 🔗 biomedizin.unibas.ch/en/newsdetai...

Department of Biomedicine🔬🧪@biomedizin· Aug 25

🎊Cheers to 25 Years of Discovery @biomedizin.unibas.ch ! Since 2000, we’ve grown into one of Switzerland’s top translational research hubs — thanks to our brilliant teams & community. We celebrated with music, laughter, science & soul. Here’s to the next 25.💙 biomedizin.unibas.ch/en/newsdetai...

Department of Biomedicine🔬🧪@biomedizin· Aug 21

🏆 Dr. Laurentz Schuhknecht @zampierilab.bsky.social wins DBM Research Prize; Johanna Nimmerfroh (Läubli Lab) earns 1st Best Presentation Award at our Summer Symposium. Congratulations! 🎉 biomedizin.unibas.ch/en/communica... #DBMPrize #BestPresentationAward #ResearchExcellence

Department of Biomedicine🔬🧪@biomedizin· Aug 20

The 2025 DBM Summer Symposium is happening today! There will be a keynote by Prof. Mustafa Khammash @eth-bsse.bsky.social , 17 short talks, and the presentation of the DBM Research Prize 2024 and the Best Presentation Award 2025. 🧬🏆 Big thanks to all involved! #DBMSymposium2025 #Science #TeamDBM