Marcin Czerwinski
@czerwinsmarcin
Researcher | glycobiology | blood groups | enviroment | photography digital and analog | Poland
β1,3-Glucosyltransferase (B3GLCT), which adds a glucose onto O-linked fucose on thrombospondin type 1 repeats (TSRs), has an unusual substrate recognition by a two GT-A fold domains. tinyurl.com/4phbkrpw #glycotime
Fabry disease: a mutation in the GLA gene leading to deficient α-galactosidase A activity, resulting in lysosomal accumulation of globotriaosylceramide (Gb3). Adamantyl-GalCer inhibits the A4GALT activity, causing a decrease in Gb3 production in fibroblasts. tinyurl.com/4cb3wrrz #glycotime
@kmikolajczyk.bsky.social demonstrates small extracellular vesicles derived from Caco-2 and HEK293T cells and functionalized with Gb3 trisaccharide (Galα1→4Galβ1→4Glc) as potent neutralizers of Shiga toxins. #glycotime tinyurl.com/29y8n5yc
Dąbrowa Namysłowska, Opolskie Voivodeship. Abandoned railway station. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford FP4+ #BelieveInFilm
Drapieżnictwo w świecie bakterii. Jak bakterie polują na inne bakterie i jak je zabijają? Jolanta Zakrzewska-Czerwińska i Kornel Milcarz przedstawiają Bdellovibrio bacteriovorus. tinyurl.com/yy2ukvjk
Miejsce, Opolskie Voivodeship. Jewish cemetery. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford FP4+ #BelieveInFilm
There are hopes that the rail line Jełowa-Namysłów (pictured) will be reopened. Right now, lots of mullein on the tracks:)
Murów, opolskie voivodeship. Abandoned railway station. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford FP4+ #BelieveInFilm
W jaki sposób pole magnetyczne Ziemi 4 miliardy lat temu spowodowało, że cząsteczki wchodzące w skład żywych organizmów są chiralne? Moje uwagi na blogu eksperymentmyslowy.pl tinyurl.com/3vh89dak
Wiatr strącił gniazdo kwiczołów, ale za pomocą duct tape i bomboniery Wedel udało się je umieścić z powrotem na drzewie.
Katarzyna Adamala and her team present "spud cells", synthetic liposomes that can replicate their genome, grow, divide, and evolve. The 90kb genome includes functions needed for resource uptake, transcription, translation, growth, genome replication, and division. tinyurl.com/yck99x55
Hraničky, Rychlebské hory/Góry Złote, Czech Republic. 📷Canon R 🔘16 mm
In our review about the α-Gal syndrome: tinyurl.com/2mbhvf66 we wrongly interpreted the data by Langley DFB et al (PNAS USA 2022, 119: e2123212119) about the structure of M86 anti-α-Gal MAb. The correction is now online: tinyurl.com/ms8ryptt We apologize😔!
Kopciuszek zwyczajny/black redstart (Phoenicurus ochruros) with 2 chicks in my carport. 📷Canon R 🔘200 mm/2.8
Z przędziwa pamięci. Filadelfia, Walnut Street, lipiec 1992. 102 stopnie Fahrenheita (39 stopni Celsjusza), wilgotność 90%. Minolta X-300, 17-40 mm, Ektachrome 100.
Slovakia, Zborov Castle. Monument of K. u. K. Landwehr-Infanterieregiment Nr. 4. 📷Canon EOS 5 🔘17-40 mm 🎞️Ilford FP4+ #BelieveInFilm
Tu moje Seiko Weekdater z komplikacją dnia tygodnia, rocznik 1964. Chodzi idealnie.
Important! Severe allergic transfusion reactions to group B/AB plasma or platelets in group O recipients are linked to α-Gal sensitization due to high titers of group B cross-reactive anti–α-Gal IgE. @alphagal-info.bsky.social @alphagal-res.bsky.social tinyurl.com/bdfyzkmb
Tu niepublikowane zdjęcia z obrony Lwowa we wrześniu 1939, fot. Witold Czerwiński.
New review on fucosylation in cancer and its role in anti-tumor immunity. Not only a tumor-promoting modification, but L-fucose also acts as a central regulator of tumor progression and immune response. Fucosyltransferases, selectins, and C-type lectins discussed! tinyurl.com/y246zx9b #glycotime
Excellent review @pavelbarahtjan.bsky.social @giodang.bsky.social about the role of glycosphingolipids in biology, particularly in cell-cell interaction. Must-read for everyone involved in GSL research! #glycotime tinyurl.com/y5ndk6cn
New study shows that hyperglycosylation is a metabolic driver of Alzheimer’s disease. Interestingly, glucosamine supplementation seems to be associated with accelerated AD progression and worsened survival. #glycotime tinyurl.com/4p2yez86
Interesting new data about neutrophil extracellular traps (NETs): red blood cells can inhibit NET formation, but not in septic individuals, due to inflammation-induced RBC desialylation and decreased expression of inhibitory Siglec-E/9 and -G on neutrophils. tinyurl.com/scdbuc8j #glycotime
"Znak". Wrocław, Park Wschodni. 📷Minolta X-300 🔘28 mm 🎞️Ilford HP5+ #BelieveInFilm
Bardejov, Słowacja. Bazylika św. Idziego/Basilica of St Giles. Canon R, 24-105 mm.
2 giugno: Gli 80 anni della Repubblica italiana. Tante auguri🤗!