Exciting to see @basecamp-research.bsky.social launch EDEN Apps, now live in Claude, helping researchers design antibiotics and prioritize vaccine targets in minutes. It’s been a pleasure collaborating with the team on this promising work across AI, biology, and therapeutic discovery.

It was a pleasure to join Penn Alumni Weekend with President J. Larry Jameson and @hamsabastani.bsky.social to discuss how @upenn.edu researchers are turning AI advances into real-world impact—from ML-driven antibiotic discovery to cross-disciplinary innovation.

A pleasure to join @pintofscience.us today in Philadelphia for “Rewriting Life: The New Era of Medicine” — a conversation on how science is reshaping the future of health with @mikelhaggadone and Pankhuri Singhal. Looking forward to it!

Recibir este Premio de Innovación de la Fundación Innovación Bankinter en su primera edición es un honor enorme y una alegría muy especial. ¡Gracias de corazón por este reconocimiento! Nos vemos el 4 de junio en Madrid.

Grateful to share my experience as a Langer Prize recipient and reflect on how early, unrestricted support fuels blue-sky ideas and helps young scientists turn bold research into real-world impact. giving.aiche.org/impact/stori...

Excited to see our paper in Drug Resistance Updates with @fleemanlab.bsky.social on protegrin-1 against colistin-resistant K. pneumoniae. Subtle arginine-loop changes can shape antimicrobial activity as much as net charge—insight into breaching resistant membranes. bit.ly/3QCmOcc

Delighted to join @aimbe-official.bsky.social’s 2026 “Views by Two” session on AI and drug targets for therapeutics with Anindita Saha of FDA. Grateful for the chance to discuss how AI is reshaping therapeutic discovery and development across science, medicine, and policy.

This week we said goodbye to Fangping after four and a half remarkable years. Thank you for your rigor, thoughtfulness, and care—and for the lasting impact you’ve had on the team and the lab. You’ll be greatly missed, and we wish you every success ahead.

Delighted to speak at @masarykuniversity.bsky.social’s Life Sciences Seminar on “Mining the Code of Life for New Antibiotics.” Brno, Mendel's home, was a fitting place to reflect on how AI's making biology searchable at scale. Many thanks to @labvacha.bsky.social for the invitation and warm welcome.

Honored that our team was named a laudeinstitute.bsky.social Moonshot Runner-up and received an Honorable Mention. Grateful for the recognition as we keep using AI to accelerate scientific discovery. Great team effort with Jacob Gardner, Mark Yatskar, Zach Ives, Yoseph Barash, and Andrew Zahrt.

Honored to speak in Madrid at the Distinguished Seminar Series hosted by cniostopcancer.bsky.social. Grateful to Óscar Fernández-Capetillo, @sabiolab.bsky.social, and the CNIO team for the invitation. AMR is a critical issue in cancer care, and CNIO’s commitment to science and impact is inspiring.

Honored to have returned last February to the University of León to receive an honorary doctorate—a true full-circle moment, from student to scientist. Deeply grateful to all who made this journey possible.

Feliz y emocionado de volver a la Universidad de León para recibir el Doctorado Honoris Causa. Un reconocimiento que siento como un abrazo a mi historia y a todas las personas que me han acompañado en el camino. Gracias de corazón. 📷Ángel López

Great hosting @basecamp-research.bsky.social Jonathan Finn & Philipp Lorenz in our lab! Inspiring discussions on evolution, programmable therapeutics, and antibiotics. Excited for what we’ll build together next.

Un honor recibir el Premio Rafael Hervada de Investigación Biomédica, uno de los más prestigiosos de España, por nuestro trabajo usando IA para acelerar el descubrimiento de antibióticos. Gracias a la Fundación San Rafael y, sobre todo, a mi equipo por hacerlo posible. 📷Marcos Míguez

Thrilled to share EDEN — a DNA-scale foundation model built with @basecamp-research.bsky.social + NVIDIA partly validated by our lab @upenn.edu . Trained on 1M+ new species, it designs novel antibiotics with 97% success. Biodiversity at scale = models that generalize and design. bit.ly/3NpMR4B

🎄The de la Fuente Lab wishes you happy holidays and a joyful, healthy, and inspiring 2026! Thank you for being part of our journey as we continue pushing science forward—together.

Absoluta maravilla esta conversación con mi amigo @pablofuente.com y una de las mejores científicas del planeta @nogaleslab.bsky.social @ucberkeleyofficial.bsky.social!

Honored to join the #VinFuturePrize Science for Life Symposia panel on AI Ethics & Safety for Humanity with brilliant minds like Hinton, @yoshuabengio.bsky.social, Valiant, Cerf, Luu, Prestes & @tobywalsh.bsky.social. Grateful to help shape the global AI ethics conversation. 🌍🤖

Thank you @asm.org for inviting me to the first ASM event in India. The IISc Global Research Symposium on the One Health Approach to Antimicrobial Resistance was a powerful example of what’s possible for AMR research there. The scientific talent here is extraordinary—excited to see what comes next.

Honored to be recognized once again among the top 1% of the world’s most highly cited researchers by @clarivate.com. This is a testament to the relentless curiosity and hard work of my team. Grateful for their dedication to pushing the frontiers of science.

Spoke at @elrig.org SCIENCE in Liverpool about moving faster on antibiotics with AI and high-qualiy training data. Amazing community. The energy in the room was the best part. You’ll Never Walk Alone.

Grateful to Elizabeth Stivison for covering our work with superstars Marcelo Torres and Anna Crysler on training AI to uncover novel antibiotics in @asbmb.bsky.social Today! Excited to see growing momentum at the intersection of AI and antibiotic discovery.

Thank you Bob Service for highlighting in @science.org our work using AI to uncover antibiotics from archaea. Grateful for the thoughtful coverage—and excited by growing interest in these ancient microbes, a distinct branch of the tree of life.

Huge thanks to @nikomccarty.bsky.social and the @asimovpress.bsky.social Podcast for the incredible gift—a book encoded in DNA! 🧬📖 A beautiful fusion of science, art, and storytelling.

My friend #EltonBrand @sixersnba.bsky.social and I at my lab's Halloween party talking about the future of AI and Sports. What are your thoughts? Do you think #RudyFernandez and #SergeiIbaka would approve of our costumes?😉 Wishing everyone a Happy Halloween! 🎃

Big day at @upenn.edu ! Honored to host my friend Elton Brand from @sixersnba.bsky.social for a deep dive into how we’re using AI to fight antimicrobial resistance. Thanks for the sharp questions and team spirit, Elton! 🧪🏀

It was an honor to participate in the third course organized by @mobilise.bsky.social @i3suporto.bsky.social, sharing experiences with incredible people. A privilege to learn, share, and connect with such an amazing group.

4/5 As a demo, we used a known antimicrobial peptide as the “key” and designed new candidates: active against multiple pathogens in vitro and reduced A. baumannii burden in mouse infection models—with good tolerability.

3/5 KCM performs across α-helices, β-sheets, mixed, and unstructured regions, delivering precise backbone geometry while staying lightweight and accessible for small labs, startups, and even classrooms.