Denise J. Cai, Ph.D.
@denisejcai
Prof. of Neuroscience @SinaiBrain · Investigating memory stability & flexibility · Advocate for open science · Mom of two littles · Amateur chef · she/her · denisecailab.com
How do memories change with time? How can we preserve memory and brain function as we age? 🧠 Thank you AFAR & MBRF for hosting this discussion on aging research and @alicelclayton.bsky.social & Sergey Young for moderating! Watch the full webinar recording here: www.youtube.com/watch?v=zT8y...
Huge congrats to Cai Lab postdoc @destyniemedeiros.bsky.social for being named a @simonsfoundation.org Junior Fellow! 🎉 Destynie is a brilliant rising star 🌟 The rigor of her science and the leadership she has built in our community impress me again and again. So well earned. Congrats, Destynie! 🧠✨
🤔 Why does prior stress make future stress hit harder? In new work led by @zachtpennington.bsky.social, the Cai Lab discovered a brain circuit that controls stress vulnerability, reshaping how the brain reacts to the next stressor. I'll be speaking about at @fens.org. Come check it out!
🎉 Congratulations to @zachtpennington.bsky.social on receiving this year's Banting Discovery Award! I worked closely with Zach when he was a postdoc in my lab and I know he is incredibly deserving of this award. Read more about his award here: psych.ubc.ca/news/zachary...
I had a fantastic time at #OptoGRC2026! Congratulations to Cai Lab member @austinbaggetta.bsky.social for winning best poster 🎉 Shout out to @tristanshuman.bsky.social & @lindsayschwarz.bsky.social for taking on the role of Vice Chairs for the next meeting 🤓
So incredibly proud to celebrate these two remarkable researchers I've had the privilege to work with! @joezaki.bsky.social and Rimi are truly deserving recipients of the #LeonLevyScholars recognition for 2026. They continue to make invaluable contributions to the field!
Reminder: Your impact is bigger than just papers ✨ At this year's Slaydies retreat, we gave each other personalized awards, holistically honoring the way we show up for each other in the neuroscience field and beyond. I'm so grateful for this community 💜
We held another incredible Memory Hub meeting at @sinaibrain.bsky.social last week, featuring @suthanalab.bsky.social and @antferrui.bsky.social, who presented their creative topic "One Rhythm, Two Species? Rethinking the functional role(s) of hippocampal theta" 🧠 🤓 It was great to see everyone!
Last week, I spent an incredible evening full of music at @onemindorg.bsky.social's 'Apollo & Psyche' celebration 🎶 Thank you for highlighting the healing power of music, One Mind. Music is such a valuable tool for mental health! Read about the event here: onemind.org/news/one-min...
🤓 Really excited to host this panel at COSYNE! Our incredible speakers Bing, Kenji, Kim & Saskia are sure to share insightful advice on making an impact in their career and community at every stage of their careers 🧑🔬 🧠
#ACNP2026 was the perfect way to start the year with some of my favorite scientists! I had a great time talking science (sometimes with my toes in the sand!) and strategizing ways to support the younger generation of scientists at the @onemindorg.bsky.social luncheon 🔬
🤓 So grateful to learn from powerhouses like Erin and @huda-akil.bsky.social during our Stories of WiN panel. We spoke about defining your legacy in science & beyond and a clear theme emerged: do science & lead according to your values. Listen here: www.storiesofwin.org/profiles/202...
The Cai & Shuman Labs threw an EPIC White Elephant party! So much holiday cheer packed into one room. We did not have a partridge in a pear tree, but we did have: 👥 25 members laughing 🥔 6 chip-bags-a-gifting 🪴 5 plants-afloating 🦫...and a capybara in a knit hat!
Wow, such an insightful and substantive open floor discussion at last night's Memory Hub meeting! 🤓 Do we need ANY of the same synapses that were active during learning to be reactivated to recall a memory? Lines have been drawn and sides taken!
Thank you to everyone who came out to the Cai-Tye Collective party at #SfN25 🎉 You all brought your amazing energy from the poster floor to the dance floor. I'm still smiling from what a great time it was!
Reunion with past and present Cai lab & Shuman lab members (and collaborators). Spending time with you guys is easily the best part of my job. @tristanshuman.bsky.social @sinaibrain.bsky.social @sfn.org
Congrats @sjo09.bsky.social! Your trailblazing engram discoveries are unforgettable. So happy that the Peter Seeburg Integrative Neuroscience Prize is honoring YOUR Era's tour @sfn.org.
Are you at #SfN25 and want VIP access to the Cai-Tye Collective event on Nov 17? Come by my lab members' posters for a bracelet! Hailey Rosenblum: Nov 15, 1-5pm PSTR040.05/BB6 Zoé Christenson Wick: Nov 17, 8am-12pm PSTR192.01/RR13 Zach Pennington: Nov 17, 1-5pm PSTR234.05/CC7
🎉 Join us on Monday for the best party of the year! The Cai-Tye Collective is throwing a bash at #SfN25 and everyone is invited! 🎉 November 17, 9pm at Parq Nightclub in San Diego. See you all there!
🧠 The Cai Lab will be at #SfN25! Be sure to stop by the poster sessions to check out Hailey's work on decision-making, @zachtpennington.bsky.social's work on stress, @zoechristensonwick.bsky.social's work on seizures, Alexa's work on cocaine seeking, and Sandra's work on context representations 🤓
We're brewing up some Halloween fun in the Cai & Shuman Labs! ⚗️🎃 Just look at all the creativity everyone poured into their costumes! We have the coolest crew 👩🔬🧪
I can’t stop replaying the #memories from our first-ever New York Memory Hub conference! So grateful to everyone who made it a success and inspired us with their research 🧠
It has been an immense honor to learn & grow with two of the greatest scientists I know: @zachtpennington.bsky.social & @joezaki.bsky.social 🧑🔬 Listen in on our conversation about mentorship, building trust and creating a safe space to disagree: neuronline.sfn.org/professional...
That's a wrap! So many incredible talks at our Memory Hub Conference today! 🧠
This morning's Memory Hub talks were fantastic! And the trainee data blitzes were 🔥
We kicked off the first annual New York Memory Hub conference this morning 🧠 Talks are in full swing!
Looking forward to tomorrow's "Perspectives Across Biology" panel at the @chanzuckerberg.bsky.social Imaging the Future meeting! If you're at CZI this week, come check it out and join the conversation 🧑🔬
Had such a great time in Napa Valley at the @onemindorg.bsky.social Summit on the Future of Mental Health Research 🧠 As a past One Mind Rising Star Awardee, it was so inspiring to connect with other awardees and see the incredible research being done by this year’s winners ⭐️