Nephrology Image When autosomal dominant polycystic kidney disease becomes atypical: aADPKD doi.org/10.1016/j.kint.2025.11.027 #NephSky #MedSky

Nephrology Image Renal hemosiderosis in paroxysmal nocturnal hemoglobinuria doi.org/10.1016/j.kint.2025.12.033 #NephSky #MedSky

Commentary What does it mean to win? Interpreting hierarchical kidney outcomes in hypertension trials doi.org/10.1016/j.kint.2026.04.012 Original article: doi.org/10.1016/j.kint.2026.02.032 #NephSky #MedSky #hypertension

Nephrology Image Light chain crystalline podocytopathy and tubulopathy doi.org/10.1016/j.kint.2025.12.030 #MedSky #NephSky

Commentary A potential role for effector T cells with Fc receptors in kidney transplant antibody-mediated rejection doi.org/10.1016/j.kint.2026.04.011 Original article: doi.org/10.1016/j.kint.2026.03.012 #MedSky #NephSky #kidneytransplantation #KTx

Nephrology Image Dual-hit cystic kidneys: ADPKD with de novo HNF1B deletion doi.org/10.1016/j.kint.2025.10.017 #NephSky #MedSky #ADPKD

Nephrology Image Neuroimaging of water intoxication: reversible cerebral edema in acute hyponatremia doi.org/10.1016/j.kint.2025.10.018 #NephSky #MedSky #hyponatremia

Commentary Beyond galactose-deficient IgA1: reconsidering IgA2 as a pathogenic driver in IgA nephropathy doi.org/10.1016/j.kint.2026.03.009 Original article: doi.org/10.1016/j.kint.2026.03.009 #MedSky #NephSky #IgAN #IgA2

Commentary Toward personalized medicine in childhood nephrotic syndrome doi.org/10.1016/j.kint.2026.04.003 Original article: doi.org/10.1016/j.kint.2026.01.026 #NephSky #MedSky #nephroticsyndrome

Nephrology Image Green discoloration of the urine doi.org/10.1016/j.kint.2025.09.038 #MedSky #NephSky

Commentary CCL2 as a microvascular “tone breaker”: inflammatory signaling and the failure of kidney autoregulation in salt-sensitive hypertension doi.org/10.1016/j.kint.2026.03.004 Original article: doi.org/10.1016/j.kint.2026.02.019 #NephSky #MedSky #hypertension

Commentary T-cell engagers mediate deep cell depletion beyond autoimmunity doi.org/10.1016/j.kint.2026.03.010 Original article: doi.org/10.1016/j.kint.2026.01.020 #NephSky #MedSky #obinutuzumab

Optimizing risk-benefit in highly sensitized kidney recipient antigen delisting increasing donor access doi.org/10.1016/j.kint.2026.04.023 #MedSky #NephSky @inserm.fr #Ktx #kidneytransplantation

Nociceptive sensory nerves induce an IL4Rαhi anti-inflammatory macrophage subset that protects against kidney ischemia-reperfusion injury doi.org/10.1016/j.kint.2026.04.022 #NephSky #MedSky #acutekidneyinjury #AKI

Therapeutic Efficacy and Antigenicity of a Novel PEGylated IgA Protease in Preclinical Models of IgA Nephropathy doi.org/10.1016/j.kint.2026.04.020 #NephSky #MedSky #OpenAccess #IgAN

Editorial: Special Report How the carbon footprint of medications can be integrated into our prescriptions doi.org/10.1016/j.kint.2026.03.005 #NephSky #MedSky #OpenAccess

Effectiveness and mechanistic effects of green mamba peptide MQ232 in an orthologous mouse model of Autosomal Dominant Polycystic Kidney Disease doi.org/10.1016/j.kint.2026.04.021 #NephSky #MedSky #OpenAccess #ADPKD

Role of the Post-translational ISGylation of Interferon Regulatory Factor 9 in Diabetes-Induced Podocyte Injury doi.org/10.1016/j.kint.2026.04.019 #NephSky #MedSky #diabetickidneydisease

Distinct proteomic signatures of urinary extracellular vesicles link to albuminuria and treatment responses in diabetic kidney disease doi.org/10.1016/j.kint.2026.04.018 #MedSky #NephSky #OpenAccess #diabetes #diabetickidneydisease

SERCA2 deficiency in tubular epithelial cells drives ferroptosis in acute kidney injury regulating endoplasmic reticulum mitochondrial calcium homeostasis via voltage dependent anion channel 1 oligomerization doi.org/10.1016/j.kint.2026.04.017 #NephSky #MedSky #AKI #acutekidneyinjury

Mitochondrial respiratory capacity in kidney podocytes is high, age-dependent, and sexually dimorphic doi.org/10.1016/j.kint.2026.04.016 #NephSky #MedSky #OpenAccess

A post hoc analysis of BLISS-LN found Belimumab plus mycophenolate mofetil improves kidney outcomes versus placebo plus mycophenolate mofetil in active lupus nephritis doi.org/10.1016/j.kint.2026.03.030 #NephSky #MedSky #lupusnephritis @osuwexmed.bsky.social @lmu.de

Clinical Journey in Translational Medicine Pegcetacoplan prophylaxis for recurrent C3 glomerulopathy with multifactorial genetic background doi.org/10.1016/j.kint.2026.03.022 #NephSky #MedSky #kidneytransplantation

XYZs of Statistics Advances in survival analyses: machine learning methods and model comparison doi.org/10.1016/j.kint.2026.02.041 #MedSky #NephSky #OpenAccess #transplantation #KTx #machinelearning #kidneytransplantation @sydney.edu.au

Nephrology Image When kidneys can’t be biopsied, skin biopsy identifies SLE relapse on dialysis doi.org/10.1016/j.kint.2025.10.015 #MedSky #NephSky #KidneyPath #PathSky

Controversy "Should atherosclerosis be the main prevention and treatment target in people with both myocardial ischemia and chronic kidney disease?" ✅Point by C Ferro & J Townend ✅Counterpoint by Z Massy ✅Editor's summary by TA Ikizler doi.org/10.1016/j.kint.2026.02.003 #NephSky #MedSky

Commentary Electronic AKI alerts at a crossroads: is it time to move on? Alessandra Orsillo and David P. Baird doi.org/10.1016/j.kint.2026.02.016 Original article: doi.org/10.1016/j.kint.2026.01.019 #NephSky #MedSky #aki #acutekidneyinjury @edinburgh-uni.bsky.social

Clinical Journey in Translational Medicine Urinary Chloride Unlocks the Mechanism of Hyponatremic Seizures doi.org/10.1016/j.kint.2026.03.021 #MedSky #NephSky

Commentary From cutoff to causality: regression discontinuity design for evaluating acute kidney injury e-alerts doi.org/10.1016/j.kint.2026.02.011 Original article: doi.org/10.1016/j.kint.2026.01.019 #MedSky #NephSky @ox.ac.uk

Commentary Evidence grows for the gut-kidney axis, but questions still remain doi.org/10.1016/j.kint.2026.02.015 Original article: doi.org/10.1016/j.ki... #NephSky #MedSky @einsteinmededu.bsky.social