🔓Take a look in our latest issue at research by Céline Olivier, Samir Amrane & co. reporting a new class of G-quadruplex ligands with anti-HIV-1 properties #medchem 📍 @univbordeaux.bsky.social doi.org/10.1039/d5md...

🔓Be sure to read #OpenAccess research from Arun K. Ghosh et al. @purduechemistry.bsky.social in our latest issue describing novel SARS-CoV-2 Mpro inhibitors containing tetrahydroisoquinoline-3-carboxamides as P2 ligands #medchem Find it in full here👇 doi.org/10.1039/d6md...

Don't miss research in our latest issue from Hongyan Li, Hongzhe Sun & co. at the University of Hong Kong showcasing the use of a bismuth drug as an antibiotic adjuvant to inhibit biofilm formation #medchem Check it out on our website🔽 doi.org/10.1039/d6md...

🔓Check out this review by Celine Cano et al. from @newcastleuni.bsky.social in our latest issue providing insights into the discovery and optimisation of DNA-PK inhibitors #medchem Read the full article below👇 doi.org/10.1039/d6md...

Take a look in our latest issue at research from Toshio Morikawa, Genzoh Tanabe & co. investigating the structure activity relationship of the indole 2-S-,3-O-bis-glucoside calanthoside #medchem 📍Kindai University doi.org/10.1039/d6md...

Be sure to read this review from Zihao Liu & Zhiguang Yang at Jilin University in our latest issue discussing the progress of histone deacetylase-based dual inhibitors in non-small cell lung cancer therapy #medchem Find their full article on our website👇 doi.org/10.1039/d6md...

🔓Don't miss #OpenAccess research in our latest issue by Ioannis K. Kostakis & co. from the University of Athens reporting novel hydroxytyrosol esters as potential anti-amyloid and neuroprotective agents for Alzheimer's disease #medchem Check it out in full here🔽 doi.org/10.1039/d6md...

📢Our latest issue is now online! Check out the research behind the cover by Oleksandr O. Grygorenko & co. from Enamine & University of Kyiv describing the structure–activity relationships in a series of dihydrouracil–JQ1 conjugates #medchem doi.org/10.1039/d6md...

Be sure to read this review by Mahdi Gallala et al. from Monastir University in our latest issue discussing the recent advances in the development of acridine-based hybrids with antiproliferative activity #medchem Find their full article below👇 doi.org/10.1039/d6md...

🔓Don't miss this #OpenAccess research in our latest issue from @danielecastagnolo.bsky.social & co. @ucl.ac.uk & @kingscollegelondon.bsky.social describing light-controlled inhibition of Gram-positive bacteria by photoswitchable amphiphilic lipids #medchem Check it out here🔽 doi.org/10.1039/d6md...

Take a look at this review from Yan Li, Honghua Zhang & co. in our latest issue looking at small-molecule therapeutics for diabetic retinopathy #medchem 📍National University of Singapore & Lanzhou University doi.org/10.1039/d6md...

Be sure to read this paper in our latest issue by Srikanta Patra, Debasis Manna et al. at IIT Guwahati & IIT Bhubaneswar addressing multidrug-resistant bacterial infections with iridium-based theragnostic agents #medchem Find it in full below👇 doi.org/10.1039/d6md...

🔓Don't miss in our latest issue #OpenAccess research by Gonzalo Rodriguez-Berriguete, Christopher J. Schofield, Geoff S. Higgins & co. @ox.ac.uk reporting structure-guided optimisation of fenofibrate-derived oxidative phosphorylation inhibitors #medchem Check it out here🔽 doi.org/10.1039/d5md...

Check out this review by Fengxia Sun, Yunfei Da et al. from Tianjin University in our latest issue discussing the targets, pharmacological properties and SAR studies of sulfone and sulfoxide-containing pharmaceuticals #medchem Read it in full on our website🔽 doi.org/10.1039/d5md...

Take a look in our latest issue at research by Patrícia Dias Fernandes & co. reporting new terpenyl–cinnamoyl–hydrazone analogues of cannabidiol with potent antinociceptive effect #medchem 📍 @ufrjoficial.bsky.social & @unifalmg.bsky.social doi.org/10.1039/d6md...

🎉We were delighted to have @fleurmferguson.bsky.social's 2026 RSC Medicinal Chemistry Emerging Investigator Lectureship presented at the Induced Proximity Modalities & Therapeutics GRC this month! A huge congratulations to Fleur again on being selected for this year's Lectureship #chemsky #medchem

📢Our latest issue is now online! Check out the article behind the cover by Nikolai Petrovsky, Janardhan Banothu & co. at NIT Calicut & Panjab University describing bisarylthiourea comprising cycloalkyl-thiophene-3-carboxylate derivatives as TLR2 agonists #medchem pubs.rsc.org/en/content/a...

📢Our latest issue is now online! Check out the research behind the cover by Paul Harris, Margaret Brimble, Alan Cameron & co. @aucklanduni.bsky.social introducing CLipPA lipid chemodiversity to enzymatically truncated polymyxin B to combat Gram -ve pathogens #medchem pubs.rsc.org/en/content/a...

Don't miss research behind the inside front cover of our latest issue by Monalisa Mukherjee, Brajendra K. Singh, Virinder S. Parmar & co. at University of Delhi reporting biocompatible de novo indolylchalcones as potential cardiovascular & wound-healing agents #medchem pubs.rsc.org/en/content/a...

📢Our latest issue is now online! Check out the research behind the front cover by Moustafa T. Gabr & co. @weillcornell.bsky.social using DNA-encoded library screening to discover a CHI3L1-targeted small molecule modulating neuroinflammation in Alzheimer's #medchem pubs.rsc.org/en/content/a...

⏳There is only one week left to get your early bird registration for the Medicinal Chemistry Summer School 2026! #medchem Don't miss your chance to increase your understanding of the factors governing modern drug discovery Register now: invt.io/1bxbmhriegz

🔓Don't miss the #OpenAccess research behind the inside front cover of our latest issue by Maria L. Di Gioia et al. from the University of Calabria presenting the integration of green synthesis and liquid–liquid extraction of lidocaine in deep eutectic solvents #medchem pubs.rsc.org/en/content/a...

📢Our latest issue is now online! Check out the review behind the cover by Konrad Kowalski & co. from University of Łódź looking at ferrocenyl ferroptosis inducers as an emerging class of anticancer agents #medchem pubs.rsc.org/en/content/a...

📢We are delighted to announce that @fleurmferguson.bsky.social (@ucsandiego.bsky.social) has been awarded the 2025 RSC Medicinal Chemistry Emerging Investigator Lectureship! Please join us in congratulating her 🎉 #medchem #chemsky Find out more about Fleur here🔽 blogs.rsc.org/md/2026/03/1...

📢Know someone worthy of the @rscbmcs.bsky.social Hall of Fame? Nominations are open for the 2026 inductee recognising a prominent chemist for outstanding, sustained contributions to areas of interest to the BMCS #chemsky #chembio #medchem Find out how to nominate🔽 www.rscbmcs.org/awards/hallo...

📢We are delighted to announce our #OpenCall for papers to our Macrocyclic Peptide & Peptidomimetics themed collection #chemsky #medchem Guest Editors: Sandro Cosconati, Cameron Pye, @danithechemist.bsky.social & Philip Thompson Deadline: 31st July 2026 Find out more🔽 www.rsc.org/publishing/j...

📢Our latest issue is now online! Check out the review behind the cover by @sculpturatus.bsky.social & co. at @uarizona.bsky.social looking at the history, synthesis and medicinal use of cantharidin, LB-100, and their analogs #medchem pubs.rsc.org/en/content/a...

📢Our first issue of 2026 is now online! 🔓Check out the #OpenAccess article behind the cover by Naoko Yoshizawa-Sugata, Hisao Masai, Yoko Yamakoshi & co. @ethz.ch reporting new water-soluble cationic porphyrins with enhanced phototoxicity to cancer cell lines #medchem pubs.rsc.org/en/content/a...

Our inside front cover is work by Renato J. S. Oliveira, Dennis Russowsky & co on synthesising fluorescent dihydropyridine–dihydropyrimidinone hybrids and their inhibition of protein kinases for anticancer applications, take a look⬇️ pubs.rsc.org/en/content/a... 📍UFRGS and Barretos Cancer Hospital🧪

This month's front cover showcases a Review article by Paul Groundwater & co discussing structural qualities of β-lactamase enzymes and the efficacy of emerging β-lactamase inhibitors against clinically significant carbapenemases, read it here👀 pubs.rsc.org/en/content/a... 📍 @sydney.edu.au 🧪