Tamara Tilburgs
@ttilburgs
The Tilburgs lab at Cincinnati Children’s investigates the fascinating mechanisms of maternal-fetal tolerance and placental immunity in humans. All views are my own.
Do you need primary HLA-G/C+ EVT or primary EVT-like cell lines from preterm, preeclampsia or healthy term pregnancies for immune cell - EVT cultures and mechanistic studies? Check out our new video protocol just published in JoVE. Made possible by Angel, Shweta, & Sayaka❤️. hubs.ly/Q04ptKq50
If you love High Dimensional Flow Cytometry, check out our new paper and R based tool: CytoBatchFlagR, to help QC your data and improve your downstream clustering and detailed analysis! doi.org/10.1002/cyto...
Great start of the week! Here I discuss my favorite topic on how the activation of decidual natural killer and T cells, through recognition of key extravillous trophoblast ligands, promotes placentation, tolerance, and immunity. Let me know what YOU think! authors.elsevier.com/sd/article/S...
Its published!!! Congratulations Zach, Shruti & Team!🥂 A story about how maternal decidual CD4 T cells are not all Treg, and that these effector memory and tissue resident memory cells recognize and respond to foreign fetal allo-antigens. doi-org.uc.idm.oclc.org/10.1111/aji....
Delighted with our new publication showing how natural microbial exposure of pregnant mice enhances T cell diversity and residency at the maternal-fetal interface and resembles human decidual immune populations with increased fidelity. www.frontiersin.org/journals/imm...
Delighted with my labs new publication on how decidual NK cells utilize the anti-microbial peptide granulysin for immune defense of placental tissues! ❤️
To keep me sane & centered, I made and fussed over this big clay pot last night! This morning, I feel refreshed and ready to focus on science! I think I may need more of this for a while...
Congratulations, Senad 🥂🥂 This CCHMC basic science research award is very well deserved and reflective of your excellent & inclusive research program!! ❤️@cincyresearch.bsky.social @cincychildrens.bsky.social
Congratulations, Dave🥂🥂 You soo deserve this senior CCHMC mentoring award!!!! Thank you for your continuous support, advice, and optimism! I would be here without this! ❤️ @cincyresearch.bsky.social @cincychildrens.bsky.social
With great sadness, I heard my PhD mentor, Frans Claas unexpectedly past away. He was extremely knowledgeable and taught me all about HLA and allo-reactive cells. But most of all, he was most generous, kind, and really funny. Frans, thank you for everything!! I am proud to be part of your legacy 💔
Excited to be at the Keystone Symposium on T cell differentiation and Innate memory!! 🔥
Journal club in the lab earlier today! Great introduction and discussion of a cool paper by the Bierle lab! We were a bit confused by placental vs pumkin weights, but hey, it's Friday! @cbierle.bsky.social
The new year starts with my 1st NIH/R01! Can't wait to expand my team and my passion for unravelling the mechanisms of placental tolerance and inflammation! Cheers You All! 🥂
Proud to see very talented trainees give an awesome talk in the CCHMC student postdoc forum!