Mark Huising

@huisinglab

Prof@UCDavis, Islet researcher, teacher of physiology and immunology, runner. Climate advocate and active transportation proponent. Cargobike Dad. Views mine.

318 Folgt656 Follower156 Posts

Bluesky

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Mark Huising@huisinglab· 9d

Just helped one of my students move apartments. 0.9 miles, couple of quick trips. The route by car would have taken more time as we could use one of the pedestrian/bike bridges in Davis.

A black Urban Arrow cargo bike loaded with two boxes, taken from the perspective of the rider. The handle bars have a cupholder with a coffee thermos, a bell, a horn and a small digital display.

An black Urban Arrow cargo bike loaded with a box and a small cabinet.

Mark Huising@huisinglab· 11d

Pleased to report we made the cover of the upcoming issue of Diabetologia for our most recent paper!! The effort was led by Ryan Hart (@ryanhart13.bsky.social). Description in the ALT text, full open acces link here: rdcu.be/fptyS

The cover image of the September issue of the scientific journal 'Diabetologia'.

The cover picture shows a high-resolution image of a live murine pancreatic islet expressing the calcium indicator GCaMP6s in every islet cell. Alpha and beta cells are pseudocoloured in hot pink and grey blue, respectively. Select single cell calcium responses to a succession of stimuli, including glucose, amino acids, somatostatin, epinephrine and potassium chloride, are highlighted. The extent and mechanisms of somatostatin inhibition of beta and alpha cell calcium and cAMP signalling have not previously been compared directly in real time. In the September issue of Diabetologia, Hart et al report that during nutrient stimulation, somatostatin inhibits insulin secretion indirectly by restraining alpha cell calcium and cAMP downstream of somatostatin receptor 2; this prevents glucagon from stimulating beta cells.

Cover credit: Ryan Hart and Mark O. Huising (UC Davis, CA, USA)

Mark Huising@huisinglab· 13d

Bonkers BBC story extolling LNG virtues in Cameron Parish - whose council president boast of 'bright future'. CP is in the most vulnerable coastal zone from sea level rise caused by burning fossil fuels. Half its people already left. But hey, they got the tax revenue... www.bbc.com/news/article...

Comic by Tom Torro of a father explaining to his kids while seated at a campfire in a cave that for a while they created a lot of profit at the expense of the planet.

Mark Huising@huisinglab· 23d

Drop off for an elementary school in 'bike-capital-of-the-world' Davis. There is nothing safe about streets where drivers turn bike lanes into high-stakes obstacle courses for kids. Providing physically protected bike lanes = making streets safer (and reduces demand for parking).

Three different cars blocking the bike lane on Sycamore Street in Davis CA in front of an elementary school next to a row of parked cars while kids on bikes have to go around in the vehicle lane.

Mark Huising@huisinglab· 24d

Final day of a great family trip, woke up to wildfire smoke, probably from the winds turning and blowing smoke south from Oregon. Not as bad as what covered the upper Midwest and Atlantic sea board this week, but nasty and depressing.

man looking out of driver side window of his car to a horizon obscured by wildfire smoke.

Mark Huising@huisinglab· 24d

Upper Sacramento River on a nymph.

Wild rainbow trout held above the water prior to release.

Rainbow trout held in the water for release.

Mark Huising@huisinglab· Jul 11

Went for a long hike on the most remote stretch of California coast, only to find this piece of plastic pollution washed up. Seems that Chevron tries to ruin absolutely everything...

Pictures of a plastic horse figurine embossed with 'Made in China, 1997, Chevron Inc. embossed on it, found washed up on a remote California beach.

Mark Huising@huisinglab· Jun 21

New paper in @diabetologiajnl.bsky.social on paracrine control of insulin secretion, led by the talented newly minted Dr. Ryan Hart (@ryanhart13.bsky.social). 1/5 doi.org/10.1007/s001...

Mark Huising@huisinglab· Jun 18

Very proud to graduate the next group of supremely talented young Doctors from my UC Davis lab!! Dr. Mohammad Pourhosseinzadeh, Dr. Michelle Chan, and Dr. Ryan Hart. They each have published creative and impactful stories - much of it coming out soon. Stay tuned!! @ucdavis.bsky.social

Three new UC Davis graduate students in full doctoral robes along with their faculty mentor

Mark Huising@huisinglab· Jun 12

Also, the ADA claims 'WE FIGHT - to end diabetes' on the account it never uses, while it's twitter lede has no such fighting words. What is it @amdiabetesassn.bsky.social ? Will you advocate for science and against OMB-2026-0034 as the @apsphysiology.bsky.social and @endocrinesociety.bsky.social do?

The lede on the American Diabetes Association on Bluesky - with zero posts - reads 'WE FIGHT to end diabetes' On the site formerly known as twitter, the ADA takes a conspicuously blander tone.

Mark Huising@huisinglab· Jun 12

The ADA CEO issues an apology on twitter (receiving 3 likes from 28k followers) for completely mishandling events at recent ADA meeting where @sekahn.bsky.social was ejected, it's bluesky account has 0 posts. Post the apology on bluesky @amdiabetesassn.bsky.social , that's where you audience is!!

Mark Huising@huisinglab· Jun 10

Another June, another crop of fantastic @ucdavis.bsky.social students who got leave their hand prints on the wall to celebrate their graduation from the Huising Lab. Congratulations to Hana, Nick, Ryan, Jacob, Frankie and visiting graduate student Jon!!

Group picture of college students who have just placed their hand prints on the wall behind them

Mark Huising@huisinglab· Jun 8

ADA sent a survey to ask how they could do better... Not censoring scientists would be a start. ADA President Elect and Scientific Sessions Chair (who I know and respect tremendously) did the right thing and resigned today. More coming. CEO Henderson next? www.medpagetoday.com/special-repo...

American Diabetes Association survey expecting no censorship as the bare minimum for a scientific organization

Mark Huising@huisinglab· Jun 6

Not just a critique, an editorial that was published in the ADA's own flagship journal Diabetes Care. The experts included several past ADA Presidents and Award winners. Page views before the ADA publicized the editorial <300, approaching 10k now. Link below, let's help the ADA get the word out.

publication metrics before and after the ADA ejected scientist for distributing paper copies of an editorial in its own journal and learned about the Streisand effect in real time.

Mark Huising@huisinglab· May 19

Biked my second grader to her field trip at the @ucdavis.bsky.social raptor center. Couple of miles mostly on protected bike lanes and along Putah Creek. Saw red-tailed hawk, turkey vulture, some hare and a frog being chased down by a hungry bird. Her classmates were driven and saw none of this...

Adult man with soft brim hat and a young girl with a red bike helmet looking at the camera, with live trees and some verdant fields in the background.

Mark Huising@huisinglab· May 18

Ran a tour of our all-electric home yesterday when the power went out. No power, no problem, as our Impulse induction cooktop has a built-in battery with enough juice for several meals ;-) #ElectrifyEverthing @damico.bsky.social @volts.wtf

Mark Huising@huisinglab· Apr 25

Huising Lab showed up at the 2026 @ucdavis.bsky.social Undergraduate Research Conference with 7 undergraduates presenting posters!! Congrats to all of them for excellent presentations, and to their graduate students for mentorship and support!!

Group picture of a diverse group of young scientists at an undergraduate research conference in a big meeting hall.

Mark Huising@huisinglab· Apr 22

Tonight at the Davis city council meeting multiple city staff just scrolling on their phones while the rest of us heard from several close friends of the student who was killed in a collision with a car - hit from behind by a driver while biking on campus last week. Such indifference.

a group of people in the audience of council chambers scrolling on their phones

Mark Huising@huisinglab· Mar 8

Writing away surrounded by American robins and cedar waxwings all morning, feasting on berries. #backyard_birding

Mark Huising@huisinglab· Jan 1

Made a bucket full of batter to bake Dutch 'Oliebollen', which we enjoyed in style with traditional Dutch weather. Happy New Year, best wishes for 2026!

A group of people gathered around a fire pit eating 'oliebollen' to celebrate the end of 2025.

Mark Huising@huisinglab· Dec 28

First big family meal prepared on this battery powered induction stove...

Holiday meal prepared on an Impulse induction cooktop

Mark Huising@huisinglab· Dec 18

Davis, CA, bike lane in front of Willett Elementary - one of the oldest bike lanes in the US. Par for course at Davis schools.

Kids on a bike running the gauntlet of cars driven by their parents' class mates blocking the bike lane in front of an elementary school

Mark Huising@huisinglab· Dec 12

Outside of my favorite friendly neighborhood brewery last night in Davis. Only one of these vehicles that likely was driven home after the consumption of alcohol weighs in excess of 6,000 pounds and has poor visibility because the hood is so tall...

An image of a frontloader cargo bike and several regular bikes parked on a parking spot next to and absolutely dwarfed by a massive black F250 pickup truck outside of Superowl, a neighborhood brewery in West Davis.

Mark Huising@huisinglab· Nov 27

Thanksgiving groceries plus awesome shopping assistant. Happy Thanksgiving!

A frontloader cargo bike with a full load of Thanksgiving groceries and a passenger.

Mark Huising@huisinglab· Nov 5

My 4th grader at a packed City Council last night asked for a safe bike/ped overpass over a busy road to connect a new development instead of needing to wait up to 2.5 minutes at a light as planned. He then asked everyone to wait with him for the duration of his comment to share how long that is.

A 4th grader giving public comment in a packed Davis city council meeting.

Mark Huising@huisinglab· Oct 29

Child pedestrian fatalities due to collisions with vehicles. US Data, source: National Highway Safety Administration

US National Highway Traffic Safety Administration indicating that Halloween is the single most deadly night for child pedestrian fatalities due to collisions with cars.

Mark Huising@huisinglab· Oct 25

Dropping off kid to a play date - it may rain so whipped out the rain cover for the first time this season.

Guy wearing a 'Bike, Just Ride It' t-shirt getting ready to ride with a child in an Urban Arrow cargo bike with a rain canopy.

Mark Huising@huisinglab· Oct 23

Biked a #bikebus to the Davis Varsity Theater to watch a free movie today with 120 Davis elementary school kids from 3 different schools). Such a blast - thankful to mayor @bapuvaitla.bsky.social for biking with us to encouraging kids to bike more and to Bike Davis for sponsoring. So much fun!!!

Davis bike bus biked to our cherished downtown Varsity theater to watch a free movie. The Mayor of Davis even rode with us and spoke to the kids. Look at how many bike we were able to fit curbside ;-)

Mark Huising@huisinglab· Oct 18

Posting for no particular reason at all.

A guy in a pink T-shirt with a unicorn that reads "alpha male" posing with a person in an inflatable unicorn costume

Mark Huising@huisinglab· Sep 16

Very proud to see the main thesis work of the intrepid Dr. Mohammad Pourhosseinzadeh come out in @pnas.org today! In this paper, Mohammad assesses how crosstalk between insulin-secreting beta and somatostatin-secreting delta cells in the islet actually happens, in near real-time. A quick thread 1/10